MMWR Recomm Rep. 1995 Jul 7;44(RR-7):1-15.
These recommendations were developed by the U.S. Public Health Service to address the increasing epidemic of human immunodeficiency virus (HIV) infection among women and their infants. The recommendations stress the importance of early diagnosis of HIV infection for the health of both women and their infants and are based on advances made in HIV-related treatment and prevention. The most significant advance for this population has been the results from a placebo-controlled, clinical trial that indicated that administration of zidovudine to HIV-infected pregnant women and their newborns reduced the risk for perinatal transmission of HIV by approximately two thirds (1). This document recommends routine HIV counseling and voluntary testing for all pregnant women and is intended to serve as guidance for health-care providers in educating women about the importance of knowing their HIV infection status. For uninfected women, such HIV counseling and testing programs can provide information that can reduce their risk for acquiring HIV; for women who have HIV infection, these programs can enable them to receive appropriate and timely medical interventions for their own health and for reducing the risk for perinatal (i.e., mother to infant) and other modes of HIV transmission. These programs also can facilitate appropriate follow-up care and services for HIV-infected women, their infants, and other family members.
这些建议由美国公共卫生服务局制定,以应对女性及其婴儿中日益严重的人类免疫缺陷病毒(HIV)感染流行情况。这些建议强调了早期诊断HIV感染对女性及其婴儿健康的重要性,并基于HIV相关治疗和预防方面取得的进展。对这一人群而言,最重大的进展是一项安慰剂对照临床试验的结果,该试验表明,给感染HIV的孕妇及其新生儿服用齐多夫定可将HIV围产期传播风险降低约三分之二(1)。本文件建议对所有孕妇进行常规HIV咨询和自愿检测,旨在为医疗保健提供者提供指导,以便向女性宣传了解自身HIV感染状况的重要性。对于未感染的女性,此类HIV咨询和检测项目可提供能降低其感染HIV风险的信息;对于感染HIV的女性,这些项目可使她们获得针对自身健康以及降低围产期(即母婴)和其他HIV传播方式风险的适当及时的医疗干预。这些项目还可为感染HIV的女性、其婴儿及其他家庭成员提供适当的后续护理和服务。