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1例患有罕见并发症的婴儿外源性类脂性肺炎,采用改良全肺灌洗术治疗。

A case of infantile exogenous lipoid pneumonia with an unusual complication managed by modified whole lung lavage.

作者信息

AlShamrani Abdullah Saeed, Alzaid Mohammed Abdullah, Fadl Sarrah M, AlFaki Mohammed Ahmed

机构信息

Pediatric Pulmonary Section, Pediatric Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Pediatric Pulmonary Section, Children Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia.

出版信息

Sudan J Paediatr. 2021;21(1):82-88. doi: 10.24911/SJP.106-1587896995.

Abstract

Exogenous lipoid pneumonia (ELP) is a known complication of lipid administration through either the nasal or oral route. ELP in paediatric patients is usually managed by discontinuing lipid administration and supportive care, including respiratory support and the use of antibiotics for secondary bacterial infection. The other modalities that remain controversial include the use of corticosteroids and clearing lipids by whole lung lavage. We report a 2-month-old infant who presented with pneumonia and whose further history revealed exposure to ghee over a month period while visiting her grandparents in the south region of Saudi Arabia. The patient was later diagnosed as having ELP and was successfully managed with modified whole lung lavage till weaned off from oxygen. Unfortunately, the case was complicated by nontuberculous , and the patient died despite maximum intervention.

摘要

外源性类脂性肺炎(ELP)是经鼻或口服途径给予脂质时已知的一种并发症。儿科患者的ELP通常通过停止脂质给药和支持性治疗来处理,包括呼吸支持以及使用抗生素治疗继发性细菌感染。其他仍存在争议的治疗方式包括使用皮质类固醇和通过全肺灌洗清除脂质。我们报告一名2个月大的婴儿,该婴儿因肺炎就诊,进一步询问病史发现其在沙特阿拉伯南部地区看望祖父母期间有一个月接触酥油的情况。该患者后来被诊断为ELP,并通过改良全肺灌洗成功治疗直至脱机。不幸的是,该病例并发了非结核性疾病,尽管进行了最大程度的干预,患者仍死亡。

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本文引用的文献

1
Exogenous lipoid pneumonia in children: A systematic review.儿童外源性类脂性肺炎:系统综述。
Paediatr Respir Rev. 2020 Feb;33:45-51. doi: 10.1016/j.prrv.2019.01.001. Epub 2019 Jan 20.
3
Assessment of Respiratory Distress by the Roth Score.用罗斯评分法评估呼吸窘迫
Clin Cardiol. 2016 Nov;39(11):636-639. doi: 10.1002/clc.22586. Epub 2016 Oct 4.

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