Andriukin A A, Marinin V F, Nastiukova E G, Dudkina L N, Niaĭkina N Iu
Ter Arkh. 1988;60(3):94-6.
An optimum scheme of prodigiosan therapy was developed for patients with steroid-dependent bronchial asthma taking account of the hormonal and immunological status. First the drug was administered at a dose of 0.1 ml of 0.005% solution, then in 3-4 days the dose was increased (in good tolerance) up to 0.2-0.4-0.8-1.0 ml. After the first administration of the drug at a dose exceeding 0.1 ml herpes virus could be activated in the body. Course therapy producing a stimulating effect on the immune system, inhibited the occurrence of autoimmune manifestations, prolonged bronchial asthma remission, permitted the reduction of retention of a maintenance dose of glucocorticoids.
考虑到激素和免疫状态，为依赖类固醇的支气管哮喘患者制定了一种最佳的灵菌红素治疗方案。首先，以0.005%溶液0.1毫升的剂量给药，然后在3-4天内（耐受性良好时）将剂量增加至0.2-0.4-0.8-1.0毫升。在首次以超过0.1毫升的剂量给药后，体内的疱疹病毒可能被激活。对免疫系统产生刺激作用的疗程治疗抑制了自身免疫表现的出现，延长了支气管哮喘的缓解期，允许减少糖皮质激素维持剂量的保留量。
