Department of Neurology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, China.
Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
BMC Neurol. 2021 Apr 21;21(1):172. doi: 10.1186/s12883-021-02173-0.
To identify the applicability of the Chinese Version of Mattis Dementia Rating Scale (DRS-CV).
The DRS-CV was administered to 483 participants, including 136 normal controls, 167 patients with mild cognition impairment (MCI), and 180 patients with Alzheimer's disease (AD). Receiver Operating Characteristic (ROC) curve was used to evaluate the sensitivity and specificity of the scale.
The scores of DRS-CV were ranked in the order of NC > MCI > mild AD > moderate AD group. Memory was the sensitive function affected at a relatively earlier stage of AD. ROC curve analysis indicated the DRS-CV total score and memory subscale showed excellent sensitivity and specificity in the discrimination between MCI from mild AD and mild AD from moderate AD, but poor sensitivity and specificity in the discrimination between MCI and NC.
The DRS-CV is useful to the early diagnosis and severity of AD, not to the early identification of MCI.
为了确定中文版 Mattis 痴呆评定量表（DRS-CV）的适用性。
对 483 名参与者进行了 DRS-CV 测试，其中包括 136 名正常对照组、167 名轻度认知障碍（MCI）患者和 180 名阿尔茨海默病（AD）患者。采用受试者工作特征（ROC）曲线评估量表的灵敏度和特异性。
DRS-CV 的评分依次为 NC > MCI > 轻度 AD > 中度 AD 组。记忆是 AD 早期阶段受影响的敏感功能。ROC 曲线分析表明，DRS-CV 总分和记忆分量表在区分 MCI 与轻度 AD 以及轻度 AD 与中度 AD 方面具有优异的灵敏度和特异性，但在区分 MCI 与 NC 方面灵敏度和特异性较差。
DRS-CV 有助于 AD 的早期诊断和严重程度评估，而不适合用于早期识别 MCI。
