Department of Community Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ghana Med J. 2020 Sep;54(3):140-145. doi: 10.4314/gmj.v54i3.3.
Cardiovascular disease (CVD) is a major cause of morbidity and hypertension is the single most important modifiable risk. Assessment of an individual's "total" predicted risk of developing a CVD event in 5- or 10-years using risk scores has been identified as an accurate measure of CVD risk. Using the latest Framingham risk score we assessed the risk among patients attending two cardiac clinics in Kumasi.
We conducted a hospital-based cross-sectional study among 441 patients attending two cardiac clinics in Kumasi, the Ashanti region of Ghana. Hospital records were reviewed and information on demography, social history and laboratory results for the lipid profile tests were extracted.
The prevalence of low, medium and high risk were 41.5%, 28.1% and 30.4% respectively. More men were at high risk compared to females (36.0% vs 23.9%, p=0.003). The risk score showed good discrimination for cardiovascular risk stratification with an overall area under the curve of 0.95; 0.97 and 0.94 for males and females respectively. The sensitivity and specificity of the Framingham risk score were 89.5% and 86.3%, respectively.
Majority of our study participants were at moderate to high risk with men being the most affected. The Framingham risk score proved to be a useful tool in predicting the 10-year total cardiovascular disease risk.
Not indicated.
心血管疾病（CVD）是发病率的主要原因，高血压是唯一最重要的可改变的危险因素。使用风险评分评估个体在 5 或 10 年内发生 CVD 事件的“总体”预测风险已被确定为 CVD 风险的准确衡量标准。我们使用最新的弗雷明汉风险评分评估了在库马西的两个心脏诊所就诊的患者的风险。
我们在加纳阿散蒂地区库马西的两个心脏诊所进行了一项基于医院的横断面研究。审查了医院记录，并提取了人口统计学、社会史和血脂谱测试的实验室结果信息。
低、中、高风险的患病率分别为 41.5%、28.1%和 30.4%。与女性相比，更多的男性处于高风险（36.0%比 23.9%，p=0.003）。风险评分在心血管风险分层方面具有良好的区分能力，总曲线下面积为 0.95；男性和女性分别为 0.97 和 0.94。弗雷明汉风险评分的敏感性和特异性分别为 89.5%和 86.3%。
我们的研究参与者大多数处于中高危风险，男性受影响最大。弗雷明汉风险评分被证明是预测 10 年总心血管疾病风险的有用工具。
未注明。
