Department of Ophthalmology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China.
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Curr Eye Res. 2021 Jul;46(7):1025-1030. doi: 10.1080/02713683.2020.1862238. Epub 2021 May 30.
: To assess the agreement between Line 3-5 raster scan mode and circular scan mode for measuring retinal vessel diameter, and to analyze the influence of scanning distance on retinal vessel diameter and agreement.: 79 healthy participants (79 eyes) were scanned with two modes. The scanning distance was defined as the distance from the center of the optic disc to the intersection of the blood vessel and the scan line on the raster image. The large superior temporal vessel was measured, with the distance between vascular wall hyperreflectivities measured to obtain vessel diameters. The degree of agreement between the line 3-5 raster scan and circular scan modes, and the effect of scanning distance on agreement and vascular diameter were assessed.: There was good agreement between line 3 subgroup and the circular scan for measuring venous and arterial diameter (venous: intraclass correlation coefficients (ICCs) = 0.87, < .001; arterial: ICCs = 0.84, < .001). Unexpectedly, diameters from the fourth raster scan were only comparable to the circular scan in measuring venous diameter (ICCs = 0.86, < .001), despite the same scanning distance between the fourth raster line and circular scan. Vessels with a scanning distance between 1400 μm - 1799 μm showed good agreement with the circular scan (venous and arterial: all ICCs ≥ 0.84, < .001). In addition, venous diameter and arterial diameter decreased with increasing distance from the optic disc center, with venous and arterial diameter decreasing by 0.02 μm/μm ( < .001) and 0.007 μm/μm ( = .02), respectively.: Arterial and venous diameter measured by the circular mode was comparable to only one scan line and two scan lines of the raster scan mode, respectively. Our study identified a difference between the two scan modes, with the difference not fully attributable to differences in scanning distance. Prospective studies reporting vascular diameter as a primary outcome should report the scan mode used.
: 评估 Line 3-5 栅格扫描模式和圆形扫描模式测量视网膜血管直径的一致性，并分析扫描距离对视网膜血管直径和一致性的影响。: 79 名健康参与者（79 只眼）分别采用两种模式进行扫描。扫描距离定义为从视盘中心到栅格图像上血管与扫描线交点的距离。测量大上方颞侧血管，测量血管壁高反射之间的距离以获得血管直径。评估 Line 3-5 栅格扫描和圆形扫描之间的一致性程度，以及扫描距离对一致性和血管直径的影响。: Line 3 亚组与圆形扫描测量静脉和动脉直径具有良好的一致性（静脉：组内相关系数（ICCs）= 0.87，<0.001；动脉：ICCs = 0.84，<0.001）。出乎意料的是，尽管第四栅线与圆形扫描的扫描距离相同，但第四栅线扫描的直径仅与圆形扫描在测量静脉直径方面具有可比性（ICCs = 0.86，<0.001）。扫描距离在 1400μm-1799μm 之间的血管与圆形扫描具有良好的一致性（静脉和动脉：所有 ICCs ≥ 0.84，<0.001）。此外，随着距视盘中心距离的增加，静脉直径和动脉直径减小，静脉和动脉直径分别减小 0.02μm/μm（<0.001）和 0.007μm/μm（=0.02）。: 圆形模式测量的动脉和静脉直径分别与栅格扫描模式的一条和两条扫描线具有可比性。我们的研究发现两种扫描模式之间存在差异，这种差异不完全归因于扫描距离的差异。报告血管直径为主要结局的前瞻性研究应报告所使用的扫描模式。
