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利用谱域光学相干断层扫描测量健康队列中视网膜血管的直径。

Diameters of retinal blood vessels in a healthy cohort as measured by spectral domain optical coherence tomography.

机构信息

Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Retina. 2013 Oct;33(9):1888-94. doi: 10.1097/IAE.0b013e31829477f2.

Abstract

PURPOSE

To describe a method for measuring the diameters of large retinal blood vessels by means of spectral domain optical coherence tomography.

METHODS

Prospective cohort study of 29 healthy subjects (58 eyes) who underwent a spectral domain optical coherence tomography examination. Two cubes of horizontal scans were placed at the superior and inferior borders of the disk to include the large temporal retinal vessels. Vessels diameters were measured, and an artery-to-vein ratio was calculated at 10 measurement points (480-1440 μm superiorly and inferiorly from the optic disk border).

RESULTS

The mean age of the study subjects was 41.45 ± 15.53 years. Patients had no ocular or systemic pathologies. The mean diameter of the retinal artery was 135.73 ± 15.64 μm and of the vein 151.32 ± 15.22 μm at the measurement point of 480 μm, with a gradual decrease to 123.01 ± 13.43 μm and 137.69 ± 13.84 μm, respectively, at 1440 μm. The artery-to-vein ratio was ≈ 0.9 at all points of measurement.

CONCLUSION

This is a new noninvasive method for retinal blood vessels diameter measurement using the spectral domain optical coherence tomography imaging modality. This method may aid in evaluation of retinal and systemic vascular diseases.

摘要

目的

描述一种通过谱域光相干断层扫描测量大视网膜血管直径的方法。

方法

对 29 名健康受试者(58 只眼)进行前瞻性队列研究,这些受试者均接受了谱域光相干断层扫描检查。在盘的上下边界处放置两个水平扫描立方体,以包括大的颞侧视网膜血管。测量血管直径,并在 10 个测量点(距视盘边界上侧和下侧 480-1440μm)计算动脉-静脉比。

结果

研究对象的平均年龄为 41.45±15.53 岁。患者无眼部或全身疾病。在 480μm 的测量点,视网膜动脉的平均直径为 135.73±15.64μm,静脉为 151.32±15.22μm,逐渐减少至 1440μm 时分别为 123.01±13.43μm 和 137.69±13.84μm。在所有测量点,动静脉比约为 0.9。

结论

这是一种使用谱域光相干断层扫描成像方式测量视网膜血管直径的新的非侵入性方法。这种方法可能有助于评估视网膜和系统性血管疾病。

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