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PCOS and Inositols: Controversial Results and Necessary Clarifications. Basic Differences Between D-Chiro and Myo-Inositol.

作者信息

Monastra Giovanni, Vucenik Ivana, Harrath Abdel Halim, Alwasel Saleh H, Kamenov Zdravko A, Laganà Antonio Simone, Monti Noemi, Fedeli Valeria, Bizzarri Mariano

机构信息

Systems Biology Group Lab (SBGLab), Sapienza University, Rome, Italy.

Department of Medical and Research Technology, University of Maryland School of Medicine, Baltimore, MD, United States.

出版信息

Front Endocrinol (Lausanne). 2021 Apr 6;12:660381. doi: 10.3389/fendo.2021.660381. eCollection 2021.

DOI:10.3389/fendo.2021.660381
PMID:33889133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8056130/
Abstract
摘要

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本文引用的文献

1
The use of D-chiro-Inositol in clinical practice.在临床实践中使用 D-手性肌醇。
Eur Rev Med Pharmacol Sci. 2021 Jan;25(1):438-446. doi: 10.26355/eurrev_202101_24412.
2
Inositols: reflections on how to choose the appropriate one for PCOS.肌醇：关于如何为多囊卵巢综合征选择合适肌醇的思考
Gynecol Endocrinol. 2020 Dec;36(12):1045-1046. doi: 10.1080/09513590.2020.1846697. Epub 2020 Nov 10.
3
Fundamental Concepts and Novel Aspects of Polycystic Ovarian Syndrome: Expert Consensus Resolutions.多囊卵巢综合征的基本概念与新进展：专家共识决议
Front Endocrinol (Lausanne). 2020 Aug 11;11:516. doi: 10.3389/fendo.2020.00516. eCollection 2020.
4
New clinical targets of d-chiro-inositol: rationale and potential applications.d-手性肌醇的新临床靶点：原理与潜在应用
Expert Opin Drug Metab Toxicol. 2020 Aug;16(8):703-710. doi: 10.1080/17425255.2020.1785429. Epub 2020 Jul 9.
5
Inositols in Polycystic Ovary Syndrome: An Overview on the Advances.多囊卵巢综合征中的肌醇：研究进展概述。
Trends Endocrinol Metab. 2020 Jun;31(6):435-447. doi: 10.1016/j.tem.2020.02.002. Epub 2020 Mar 9.
6
Risk of reduced intestinal absorption of myo-inositol caused by D-chiro-inositol or by glucose transporter inhibitors.D-手性肌醇或葡萄糖转运体抑制剂导致肌醇肠道吸收减少的风险。
Expert Opin Drug Metab Toxicol. 2019 Sep;15(9):697-703. doi: 10.1080/17425255.2019.1651839. Epub 2019 Aug 8.
7
The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios.40:1 肌醇/D-手性肌醇血浆比值能够恢复多囊卵巢综合征患者的排卵：与其他比值的比较。
Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5512-5521. doi: 10.26355/eurrev_201906_18223.
8
Myo-inositol and D-chiro-inositol (40:1) reverse histological and functional features of polycystic ovary syndrome in a mouse model.肌醇和 D-手性肌醇（40:1）逆转了多囊卵巢综合征小鼠模型的组织学和功能特征。
J Cell Physiol. 2019 Jun;234(6):9387-9398. doi: 10.1002/jcp.27623. Epub 2018 Oct 14.
9
Inositol in Polycystic Ovary Syndrome: Restoring Fertility through a Pathophysiology-Based Approach.多囊卵巢综合征中的肌醇：基于病理生理学的方法恢复生育能力。
Trends Endocrinol Metab. 2018 Nov;29(11):768-780. doi: 10.1016/j.tem.2018.09.001. Epub 2018 Sep 27.
10
Myo-inositol supplementation reduces the amount of gonadotropins and length of ovarian stimulation in women undergoing IVF: a systematic review and meta-analysis of randomized controlled trials.补充肌醇可减少接受体外受精女性的促性腺激素量及卵巢刺激时间：一项随机对照试验的系统评价和荟萃分析
Arch Gynecol Obstet. 2018 Oct;298(4):675-684. doi: 10.1007/s00404-018-4861-y. Epub 2018 Aug 4.