Mohammadkarimi Vahid, Ahsant Samaneh, Bagheri Mohammad Hadi, Jalli Reza, Hosseinipour Ali, Masoompour Seyed Masoom
Assistant Professor, Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Resident, Student Research Committee AND Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
ARYA Atheroscler. 2020 Sep;16(5):220-225. doi: 10.22122/arya.v16i5.2040.
We evaluated to see if the algorithmic approach of pulmonary embolism (PE) [Wells' score, followed by D-dimer test and computed tomography pulmonary angiography (CTPA)] is appropriately followed in teaching hospitals of Shiraz, Iran.
From October 2012 to October 2013, we prospectively calculated Wells' score for all patients who underwent CTPA with clinical suspicion to PE; patients with low probability who had not checked the D-dimer or had low level of D-dimer were considered as non-adherent to the guideline and those with high level of D-dimer or high probability of Wells' score were labeled as adherent to the PE guideline. CTPA scans were independently reported by two radiologists.
During study period, 364 patients underwent CTPA to rule out PE, of which 125 (34.3%) had Wells' score > 4 (high probable risk) and 239 had Wells' score ≤ 4. Amongst low probable risk patients (Wells' score ≤ 4), only 32 patients had undergone the D-dimer test (23 patients had high level of D-dimer). Based on the algorithmic approach, patients with suspected PE, patients with high probability (125 patients), and patients with low probability with elevated D-dimer level (23 patients) were considered as adherent to the PE guideline; consequently, the total adherence to PE guideline was 148 out of 364 (40.6%).
We followed the algorithmic approach guideline in about 40.0% of cases; however, we should pay more attention to the algorithmic approach in patients with suspected PE.
我们评估了伊朗设拉子的教学医院是否适当遵循了肺栓塞(PE)的算法方法(Wells评分,随后进行D-二聚体检测和计算机断层扫描肺动脉造影(CTPA))。
2012年10月至2013年10月,我们前瞻性地计算了所有因临床怀疑PE而接受CTPA检查的患者的Wells评分;未检查D-二聚体或D-二聚体水平低的低概率患者被视为未遵循指南,而D-二聚体水平高或Wells评分高概率的患者被标记为遵循PE指南。CTPA扫描由两名放射科医生独立报告。
在研究期间,364例患者接受CTPA以排除PE,其中125例(34.3%)的Wells评分>4(高风险概率),239例的Wells评分≤4。在低风险概率患者(Wells评分≤4)中,只有32例患者进行了D-二聚体检测(23例患者D-二聚体水平高)。根据算法方法,疑似PE患者、高概率患者(125例患者)和D-二聚体水平升高的低概率患者(23例患者)被视为遵循PE指南;因此,364例患者中共有148例(40.6%)遵循PE指南。
我们在约40.0%的病例中遵循了算法方法指南;然而,我们应更加关注疑似PE患者的算法方法。