Department of Nursing and Midwifery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.
Pan Afr Med J. 2021 Jan 20;38:65. doi: 10.11604/pamj.2021.38.65.27366. eCollection 2021.
The long-term effects of the severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) are not well understood. This rapid review was aimed at synthesizing evidence on the long-term effects of the SARS-CoV-2 infection among survivors. We considered both randomised controlled trials and non-randomised studies eligible for inclusion in this review. The following databases were searched: PubMed, Scopus, Cochrane library, Google Scholar, and the World Health Organization (WHO) COVID-19 database. The reference lists of all the included studies were also searched. Two authors independently screened the search outputs and reviewed full texts of potentially eligible articles. Data extraction was done by one author and checked by a second author. A meta-analysis was not conducted due to heterogeneity among the included studies. Results are presented narratively. Eleven studies met our inclusion criteria. All these studies were conducted in high-income countries. Study findings demonstrate that COVID-19 survivors can experience persistent symptoms after recovering from their initial illness, especially among previously hospitalized persons. The majority of symptoms reported were fatigue, shortness of breath, cough, and sleep disorders. Mental conditions, such as depression and anxiety disorders, were also reported. In conclusion, this study showed that COVID-19 survivors can experience persistent symptoms after recovering from their initial illness. Therefore, there is a need for a long-term follow-up of COVID-19 patients and rehabilitation services for survivors. More research is needed in this area, especially in Africa.
严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 的长期影响尚不清楚。本快速综述旨在综合 SARS-CoV-2 感染幸存者的长期影响的证据。我们考虑了随机对照试验和非随机研究有资格纳入本综述。检索了以下数据库:PubMed、Scopus、Cochrane 图书馆、Google Scholar 和世界卫生组织 (WHO) COVID-19 数据库。还检索了所有纳入研究的参考文献列表。两位作者独立筛选搜索结果并审查了可能符合条件的文章的全文。由一位作者进行数据提取,由第二位作者进行检查。由于纳入研究之间存在异质性,因此未进行荟萃分析。结果以叙述方式呈现。符合纳入标准的研究有 11 项。所有这些研究都是在高收入国家进行的。研究结果表明,COVID-19 幸存者在从最初的疾病中康复后可能会出现持续的症状,尤其是在以前住院的人群中。报告的大多数症状是疲劳、呼吸急促、咳嗽和睡眠障碍。还报告了精神状况,如抑郁和焦虑障碍。总之,本研究表明 COVID-19 幸存者在从最初的疾病中康复后可能会出现持续的症状。因此,需要对 COVID-19 患者进行长期随访,并为幸存者提供康复服务。需要在这一领域进行更多的研究,特别是在非洲。