The antibacterial effect of mouthwash on the levels of salivary in dental plaque: a randomized, single-blind, placebo-controlled trial.

BACKGROUND AND OBJECTIVES

Dental caries is one of the most common chronic diseases around the world. Inhibitory effects of bark extract has been proved on tooth decay both and by using free sugar chewing gum. This research aimed to examine the effect of bark mouth-wash on the prevalence of in dental plaque.

MATERIALS AND METHODS

This crossover, placebo-controlled, clinical trial study, was performed on a total of twenty participants (aged 18 to 35 years) in both control and intervention groups and four phases. The prevalence of was measured in a certain volume of volunteer's dental plaque at the beginning of the project (phase 1), after the first prescription (phase 2), following the washout period (phase 3) and finally after the second prescription (phase 4) by culture on bacteriology medium. Plaque index and saliva sampling were carried out in follow-up visits by a dentist. The data were analyzed using T-Test (paired and independent) quantitatively.

RESULTS

There was a significant difference in frequency in dental plaque between when the participants used mouthwash and when they washed out or used a placebo (p<0.005). Results also showed a significant difference between and Placebo groups in the mean count of saliva bacterial colony counts after oral administration in the first and second time (P<0.001 and P<0.004, respectively).

CONCLUSION

The current trial showed that %0.3 mouthwash tends to decrease the number of in dental plaque significantly. Therefore, its mass production and release to the oral health community are suggested. However, further studies with larger sample sizes and varying treatment are required to substantiate the findings of this study.