六种印度植物提取物对变形链球菌抗菌效果的比较评估
Comparative Evaluation of Antibacterial Efficacy of Six Indian Plant Extracts against Streptococcus Mutans.
作者信息
Jain Isha, Jain Pankaj, Bisht Dakshina, Sharma Alosha, Srivastava Binita, Gupta Nidhi
机构信息
Sr. Lecturer, Department of Pedodontics and Preventive Dentistry, ITS Dental College , Ghaziabad, India .
Reader, Department of Oral Pathology, ITS Dental College , Ghaziabad, India .
出版信息
J Clin Diagn Res. 2015 Feb;9(2):ZC50-3. doi: 10.7860/JCDR/2015/11526.5599. Epub 2015 Feb 1.
INTRODUCTION
To assess the antimicrobial efficacy of six plant extracts of Indian origin often used as traditional medicine against standard strains of Streptococcus mutans.
MATERIALS AND METHODS
The antimicrobial activity of six plant extracts was determined by the agar well diffusion method. The minimum inhibitory concentration (MIC) for the crude (raw), Organic solvent based, aqueous extracts was determined by the agar well diffusion method.
RESULTS
Out of all the six extracts evaluated, organic solvent based and aqueous extracts of all the extracts were found to have variable antimicrobial activities against the oral pathogen. The crude extract of Garlic was the most effective against Streptococcus mutans with the highest zone of inhibition (24.62 mm) followed by the aqueous extract of Amla (19.47mm) and organic solvent based extract of Ginger (18.76 mm).
CONCLUSION
Despite of the fact that the extracts were not pure compounds and antimicrobial results were obtained. This recommends the potency of these extracts. The figment of the derivation of antimicrobial compounds from plants seems lucrative as it will lead to the development of a phytomedicine to act against microbes.
引言
评估六种常用于传统医学的印度原产植物提取物对变形链球菌标准菌株的抗菌效果。
材料与方法
采用琼脂孔扩散法测定六种植物提取物的抗菌活性。通过琼脂孔扩散法测定粗提物（原液）、有机溶剂提取物和水提取物的最低抑菌浓度（MIC）。
结果
在评估的所有六种提取物中，所有提取物的有机溶剂提取物和水提取物对口腔病原体均具有不同程度的抗菌活性。大蒜粗提物对变形链球菌最有效，抑菌圈最大（24.62毫米），其次是印度醋栗水提取物（19.47毫米）和生姜有机溶剂提取物（18.76毫米）。
结论
尽管提取物并非纯化合物，但仍获得了抗菌结果。这表明这些提取物具有效力。从植物中提取抗菌化合物似乎前景广阔，因为这将促使开发出对抗微生物的植物药。
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