播散性单纯疱疹病毒2型作为妊娠并发症
Disseminated herpes simplex virus 2 as a complication of pregnancy.
作者信息
Bougioukas Lauren, Psoinos Rachel B C, Jones David C, Morris Erin A, Hale Andrew J
机构信息
Larner College of Medicine, University of Vermont, Burlington, VT, United States.
University of Vermont Medical Center, United States.
出版信息
IDCases. 2021 Mar 31;24:e01107. doi: 10.1016/j.idcr.2021.e01107. eCollection 2021.
Disseminated herpes simplex virus 2 (HSV-2) infection, is a rare but devastating infection in pregnancy women. We present the case of a 30-year-old gravida 3, para 2-0-0-2, at 26 weeks 2 days gestation who presented with eleven days of vague and indolent symptoms before a diagnosis of disseminated HSV-2 infection with associated hepatitis was made. While the patient clinically improved with empiric acyclovir treatment, possibility of significant harm to the fetus remained, and the patient request elective termination. The authors review the epidemiology, diagnosis, treatment, and prognosis of disseminated HSV-2 infection in pregnancy.
播散性单纯疱疹病毒2型（HSV-2）感染是妊娠期女性中一种罕见但极具破坏性的感染。我们报告一例30岁、孕3产2（2-0-0-2）的孕妇，在妊娠26周2天时，出现了11天的模糊且隐匿的症状，之后才被诊断为播散性HSV-2感染并伴有肝炎。虽然患者经经验性阿昔洛韦治疗后临床症状有所改善，但对胎儿造成重大伤害的可能性依然存在，且患者要求选择性终止妊娠。作者回顾了妊娠期播散性HSV-2感染的流行病学、诊断、治疗及预后。
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