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生殖器疱疹:诊断、治疗与预防

Herpes Genitalis: Diagnosis, Treatment and Prevention.

作者信息

Sauerbrei A

机构信息

Institut für Virologie und Antivirale Therapie, Konsiliarlabor für HSV und VZV, Universitätsklinikum Jena, Jena, Germany.

出版信息

Geburtshilfe Frauenheilkd. 2016 Dec;76(12):1310-1317. doi: 10.1055/s-0042-116494. Epub 2016 Oct 18.

DOI:10.1055/s-0042-116494
PMID:28017972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5177552/
Abstract

Herpes genitalis is caused by the herpes simplex virus type 1 or type 2 and can manifest as primary or recurrent infection. It is one of the most common sexually transmitted infections and due to associated physical and psychological morbidity it constitutes a considerable, often underestimated medical problem. In addition to providing the reader with basic knowledge of the pathogen and clinical presentation of herpes genitalis, this review article discusses important aspects of the laboratory diagnostics, antiviral therapy and prophylaxis. The article is aimed at all health-care workers managing patients with herpes genitalis and attempts to improve the often suboptimal counselling, targeted use of laboratory diagnostics, treatment and preventive measures provided to patients.

摘要

生殖器疱疹由1型或2型单纯疱疹病毒引起,可表现为原发性或复发性感染。它是最常见的性传播感染之一,由于相关的生理和心理疾病,它构成了一个相当大的、常常被低估的医学问题。除了向读者提供生殖器疱疹的病原体和临床表现的基本知识外,这篇综述文章还讨论了实验室诊断、抗病毒治疗和预防的重要方面。本文旨在为所有诊治生殖器疱疹患者的医护人员提供帮助,并试图改善对患者的咨询、实验室诊断的针对性应用、治疗和预防措施,目前这些方面往往不尽人意。

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Herpes Genitalis: Diagnosis, Treatment and Prevention.生殖器疱疹:诊断、治疗与预防
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本文引用的文献

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The Presentation, Diagnosis, and Treatment of Sexually Transmitted Infections.性传播感染的表现、诊断和治疗。
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Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance.对1973年至2014年间300多株临床分离株的单纯疱疹病毒1型胸苷激酶和DNA聚合酶基因进行序列分析,发现了可能与抗病毒耐药性发展相关的新突变。
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Int J STD AIDS. 2015 Oct;26(11):763-76. doi: 10.1177/0956462415580512. Epub 2015 Apr 9.