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一名绝经后女性的子宫内膜卵黄囊瘤:病例报告及文献复习

Yolk sac tumor of the endometrium in a post-menopausal woman: Case report and review of the literature.

作者信息

Sinha Risha, Bustamante Bethany, Truskinovsky Alexander, Goldberg Gary L, Shih Karin K

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Zucker School of Medicine at Hofstra/Northwell, Northwell Health, 270-05 76 Avenue, Suite C-221, New Hyde Park, NY 11040, United States.

Department of Pathology, Northwell Health, 6 Ohio Drive, Suite 202, Lake Success, NY 11042, United States.

出版信息

Gynecol Oncol Rep. 2021 Mar 16;36:100748. doi: 10.1016/j.gore.2021.100748. eCollection 2021 May.

DOI:10.1016/j.gore.2021.100748
PMID:33889702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8050376/
Abstract

•Seven of eighteen postmenopausal female endometrial YST cases were pure YST.•IHC supports somatic tumor cell -differentiation yielding extra-gonadal YST.•Studying genetic alterations in endometrial YST may elucidate its histiogenesis.

摘要

•18例绝经后女性子宫内膜卵黄囊瘤病例中有7例为单纯卵黄囊瘤。

•免疫组化支持体细胞肿瘤细胞分化产生性腺外卵黄囊瘤。

•研究子宫内膜卵黄囊瘤的基因改变可能有助于阐明其组织发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa5c/8050376/2f513b9a1e85/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa5c/8050376/b41b6f358914/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa5c/8050376/2f513b9a1e85/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa5c/8050376/b41b6f358914/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa5c/8050376/2f513b9a1e85/gr2.jpg

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本文引用的文献

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Mixed Germ Cell Tumor of the Endometrium: A Case Report and Literature Review.子宫内膜混合性生殖细胞肿瘤:一例报告及文献复习
Open Med (Wars). 2020 Feb 4;15:65-70. doi: 10.1515/med-2020-0010. eCollection 2020.
2
Germ Cell Tumors of the Female Genital Tract.女性生殖道生殖细胞肿瘤
Surg Pathol Clin. 2019 Jun;12(2):621-649. doi: 10.1016/j.path.2019.01.005.
3
Extragonadal Yolk Sac Tumor Limited to the Myometrium: Report of a Case With Potential Fertility Preservation and Molecular Analysis Suggesting Germ Cell Origin.
局限于子宫肌层的卵巢外卵黄囊瘤:一例有潜在生育力保存可能的病例报道及提示生殖细胞来源的分子分析。
Int J Gynecol Pathol. 2020 May;39(3):247-253. doi: 10.1097/PGP.0000000000000601.
4
Unusual Presentations of Gynecologic Tumors: Extragonadal Yolk Sac Tumor of the Vulva.妇科肿瘤的不寻常表现:外阴性腺外卵黄囊瘤
Arch Pathol Lab Med. 2017 Feb;141(2):293-297. doi: 10.5858/arpa.2016-0151-SA. Epub 2016 Dec 13.
5
Primary Endometrial Yolk Sac Tumor With Endodermal-Intestinal Differentiation Masquerading as Metastatic Colorectal Adenocarcinoma.具有内胚层-肠分化的原发性子宫内膜卵黄囊瘤伪装成转移性结直肠癌
Int J Gynecol Pathol. 2016 Jul;35(4):316-20. doi: 10.1097/PGP.0000000000000236.
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Primary yolk sac tumor concomitant with carcinosarcoma originating from the endometrium: case report.原发性卵黄囊瘤合并子宫内膜来源的癌肉瘤:病例报告
Gynecol Oncol. 2006 Oct;103(1):368-71. doi: 10.1016/j.ygyno.2006.04.024. Epub 2006 Jun 30.
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Primary endodermal sinus tumor of the endometrium presenting as "recurrent" endometrial adenocarcinoma.表现为“复发性”子宫内膜腺癌的原发性子宫内膜内胚窦瘤
Gynecol Oncol. 2001 Jan;80(1):93-5. doi: 10.1006/gyno.2000.6011.
8
Overexpression or mutation of the p53 tumor suppressor gene does not occur in malignant ovarian germ cell tumors.恶性卵巢生殖细胞肿瘤中不存在p53肿瘤抑制基因的过表达或突变。
Cancer. 1995 Jul 15;76(2):291-5. doi: 10.1002/1097-0142(19950715)76:2<291::aid-cncr2820760220>3.0.co;2-2.
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Adjuvant therapy of ovarian germ cell tumors with cisplatin, etoposide, and bleomycin: a trial of the Gynecologic Oncology Group.顺铂、依托泊苷和博来霉素用于卵巢生殖细胞肿瘤的辅助治疗:妇科肿瘤学组的一项试验
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