Wythenshawe Hospital, Manchester University Hospital NHS Foundation Trust, Manchester, UK.
Manchester Medical School, University of Manchester, Manchester, UK.
Anaesthesia. 2021 Aug;76(8):1051-1059. doi: 10.1111/anae.15489. Epub 2021 Apr 23.
General anaesthesia is known to achieve the shortest decision-to-delivery interval for category-1 caesarean section. We investigated whether the COVID-19 pandemic affected the decision-to delivery interval and influenced neonatal outcomes in patients who underwent category-1 caesarean section. Records of 562 patients who underwent emergency caesarean section between 1 April 2019 and 1 July 2019 in seven UK hospitals (pre-COVID-19 group) were compared with 577 emergency caesarean sections performed during the same period during the COVID-19 pandemic (1 April 2020-1 July 2020) (post-COVID-19 group). Primary outcome measures were: decision-to-delivery interval; number of caesarean sections achieving decision-to-delivery interval < 30 min; and a composite of adverse neonatal outcomes (Apgar 5-min score < 7, umbilical arterial pH < 7.10, neonatal intensive care unit admission and stillbirth). The use of general anaesthesia decreased significantly between the pre- and post-COVID-19 groups (risk ratio 0.48 (95%CI 0.37-0.62); p < 0.0001). Compared with the pre-COVID-19 group, the post-COVID-19 group had an increase in median (IQR [range]) decision-to-delivery interval (26 (18-32 [4-124]) min vs. 27 (20-33 [3-102]) min; p = 0.043) and a decrease in the number of caesarean sections meeting the decision-to-delivery interval target of < 30 min (374/562 (66.5%) vs. 349/577 (60.5%); p = 0.02). The incidence of adverse neonatal outcomes was similar in the pre- and post-COVID-19 groups (140/568 (24.6%) vs. 140/583 (24.0%), respectively; p = 0.85). The small increase in decision-to-delivery interval observed during the COVID-19 pandemic did not adversely affect neonatal outcomes.
全身麻醉可实现 1 类剖宫产最短的决策至分娩间隔。我们研究了 COVID-19 大流行是否影响了 1 类剖宫产的决策至分娩间隔,并影响了接受剖宫产的新生儿的结局。比较了 2019 年 4 月 1 日至 2019 年 7 月 1 日期间在英国 7 家医院接受急诊剖宫产的 562 例患者的记录(COVID-19 前组)和 2020 年 4 月 1 日至 2020 年 7 月 1 日期间 COVID-19 大流行期间接受的 577 例急诊剖宫产(COVID-19 后组)。主要结局指标是:决策至分娩间隔;达到<30 分钟决策至分娩间隔的剖宫产术数;以及不良新生儿结局的综合指标(Apgar 5 分钟评分<7,脐动脉 pH 值<7.10,新生儿重症监护病房入院和死产)。COVID-19 前和 COVID-19 后组之间全身麻醉的使用率明显下降(风险比 0.48(95%CI 0.37-0.62);p<0.0001)。与 COVID-19 前组相比,COVID-19 后组的决策至分娩间隔中位数(IQR [范围])增加(26(18-32 [4-124])分钟比 27(20-33 [3-102])分钟;p=0.043),达到<30 分钟决策至分娩间隔目标的剖宫产术数减少(374/562(66.5%)比 349/577(60.5%);p=0.02)。COVID-19 前和 COVID-19 后组新生儿不良结局的发生率相似(分别为 140/568(24.6%)和 140/583(24.0%);p=0.85)。COVID-19 大流行期间观察到的决策至分娩间隔的微小增加并未对新生儿结局产生不利影响。