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新型冠状病毒肺炎对剖宫产全身麻醉率的影响。英格兰西北部六家医院的横断面分析。

The effect of COVID-19 on general anaesthesia rates for caesarean section. A cross-sectional analysis of six hospitals in the north-west of England.

机构信息

Department of Anaesthesia and Peri-operative Medicine, University of Manchester, Saint Mary's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

Department of Anaesthesia, Peri-operative and Intensive Care Medicine, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

出版信息

Anaesthesia. 2021 Mar;76(3):312-319. doi: 10.1111/anae.15313. Epub 2020 Nov 2.

Abstract

At the onset of the global pandemic of COVID-19 (SARS-CoV-2), guidelines recommended using regional anaesthesia for caesarean section in preference to general anaesthesia. National figures from the UK suggest that 8.75% of over 170,000 caesarean sections are performed under general anaesthetic. We explored whether general anaesthesia rates for caesarean section changed during the peak of the pandemic across six maternity units in the north-west of England. We analysed anaesthetic information for 2480 caesarean sections across six maternity units from 1 April to 1 July 2020 (during the pandemic) and compared this information with data from 2555 caesarean sections performed at the same hospitals over a similar period in 2019. Primary outcome was change in general anaesthesia rate for caesarean section. Secondary outcomes included overall caesarean section rates, obstetric indications for caesarean section and regional to general anaesthesia conversion rates. A significant reduction (7.7 to 3.7%, p < 0.0001) in general anaesthetic rates, risk ratio (95%CI) 0.50 (0.39-0.93), was noted across hospitals during the pandemic. Regional to general anaesthesia conversion rates reduced (1.7 to 0.8%, p = 0.012), risk ratio (95%CI) 0.50 (0.29-0.86). Obstetric indications for caesarean sections did not change (p = 0.17) while the overall caesarean section rate increased (28.3 to 29.7%), risk ratio (95%CI) 1.02 (1.00-1.04), p = 0.052. Our analysis shows that general anaesthesia rates for caesarean section declined during the peak of the pandemic. Anaesthetic decision-making, recommendations from anaesthetic guidelines and presence of an on-site anaesthetic consultant in the delivery suite seem to be the key factors that influenced this decline.

摘要

在 COVID-19(SARS-CoV-2)全球大流行之初,指南建议在剖宫产时优先使用区域麻醉而不是全身麻醉。英国的国家数据表明,超过 17 万例剖宫产中有 8.75%是在全身麻醉下进行的。我们探讨了在英格兰西北部的六家产科单位中,大流行期间剖宫产全身麻醉率是否发生了变化。我们分析了 2020 年 4 月 1 日至 7 月 1 日期间六家产科单位的 2480 例剖宫产的麻醉信息,并将这些信息与 2019 年同期在同一医院进行的 2555 例剖宫产的数据进行了比较。主要结局是剖宫产全身麻醉率的变化。次要结局包括总剖宫产率、剖宫产的产科指征和区域麻醉到全身麻醉的转换率。在大流行期间,各医院的全身麻醉率显著下降(7.7%降至 3.7%,p<0.0001),风险比(95%CI)为 0.50(0.39-0.93)。区域麻醉到全身麻醉的转换率也降低(1.7%降至 0.8%,p=0.012),风险比(95%CI)为 0.50(0.29-0.86)。剖宫产的产科指征没有改变(p=0.17),而总的剖宫产率增加(28.3%升至 29.7%),风险比(95%CI)为 1.02(1.00-1.04),p=0.052。我们的分析表明,在大流行高峰期剖宫产的全身麻醉率下降了。麻醉决策、麻醉指南的建议以及分娩室中是否有现场麻醉顾问似乎是影响这一下降的关键因素。

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