Department of Urology, Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey.
Department of Radiology, Istanbul University-Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey.
Int J Clin Pract. 2021 Jul;75(7):e14264. doi: 10.1111/ijcp.14264. Epub 2021 May 4.
To investigate the relationship between ureteral wall thickness (UWT) and other variables of patients who underwent extracorporeal shock wave lithotripsy (SWL) in the primary treatment of the ureteral stone above the iliac crest level.
A total of 147 patients aged 18 years and older, who underwent SWL in our clinic between December 2016 and December 2019 for the treatment of ureteral stones above the iliac crest level and had non-contrast enhanced abdominal computed tomography scans before the procedure were included in the clinical study. The results were evaluated at 3 months after SWL. The absence of residual fragments was considered as stone-free status, and the existence of any size residual fragment was considered as treatment failure.
In our study, the mean age of the patients was 42.4 ± 12.8 years, and the stone-free rate was 92.5%. The median transverse stone size was 7.5 mm (min 2.8-max 15), and the median UWT was 4.2 mm (1-8.7). In the multivariate analysis, UWT (P = .002) and multiple stone presence (P = .027) were found to be independent factors affecting stone-free status. In the receiver operating characteristic curve analysis, the optimal threshold value for UWT was determined as 5.25 mm.
We found that UWT was the most important independent variable associated with increased failure in SWL treatment. The presence of multiple stones was another independent factor that increased the failure rates. Using SWL technology through experience accumulated with the mechanical hardware of the machine, we can select patients who are more suitable for this treatment and improve treatment outcomes.
研究体外冲击波碎石术(SWL)治疗髂嵴以上输尿管结石患者的输尿管壁厚度(UWT)与其他变量之间的关系。
本临床研究共纳入 147 例年龄在 18 岁及以上、因髂嵴以上输尿管结石于 2016 年 12 月至 2019 年 12 月在我院行 SWL 治疗且术前均行腹部非增强 CT 扫描的患者。结果在 SWL 后 3 个月进行评估。无残留碎片被认为是无结石状态,存在任何大小的残留碎片被认为是治疗失败。
在本研究中,患者的平均年龄为 42.4±12.8 岁,无结石率为 92.5%。结石的中位横径为 7.5mm(最小 2.8mm,最大 15mm),UWT 的中位数为 4.2mm(1-8.7mm)。多变量分析显示,UWT(P=0.002)和多发结石(P=0.027)是影响无结石状态的独立因素。在受试者工作特征曲线分析中,UWT 的最佳截断值确定为 5.25mm。
我们发现 UWT 是与 SWL 治疗失败增加最相关的独立变量。多发结石的存在是另一个增加失败率的独立因素。通过使用 SWL 技术和积累的机器机械硬件经验,我们可以选择更适合这种治疗的患者,提高治疗效果。