Suppr超能文献

与快克可卡因早期使用相关的因素:一项巴西多中心研究。

Factors associated with crack-cocaine early initiation: a Brazilian multicenter study.

机构信息

Department of Psychiatry, Federal University of São Paulo (UNIFESP), São Paulo, Brazil, Rua Major Maragliano, 241, SP, 04017030, São Paulo, Brazil.

Reference Center for Alcohol, Tobacco and Other Drugs (CRATOD), São Paulo State Secretary of Health, Rua Prates, 165, 01121000, São Paulo, Brazil.

出版信息

BMC Public Health. 2021 Apr 23;21(1):781. doi: 10.1186/s12889-021-10769-x.

Abstract

BACKGROUND

Crack-cocaine dependence is a serious public health issue, related to several psychiatric and psychosocial problems. Crack-cocaine users are usually embedded in a context of great social vulnerability, often associated with violence, poverty, family conflict and easy and early access to alcohol, tobacco and other drugs.

METHODS

This cross-sectional study enrolled a consecutive sample of 577 patients admitted to 20 therapeutic communities located in Southern Brazil, between September 2012 and September 2013. A structured interview assessed life-time exposure to risk and protective factors for drug use, such as parental monitoring in childhood, deviant behaviors and peer pressure.

RESULTS

Presence of family conflict (p = 0.002), maltreatment (p = 0.016), and deviant behavior prior to age 15 in a bivariate analysis predicted an earlier age of crack-cocaine initiation, whereas adolescents experiencing parental monitoring during adolescence started use later (p < 0.001). In the multivariate model, perceptions related to ease of access of illicit drugs (marijuana: p = 0.028, 95% CI = - 3.81, - 0.22; crack-cocaine: p < 0.001, 95% CI = - 7.40, - 4.90), and deviant behavior (threatening someone with a gun: p = 0.028, 95% CI = - 2.57, - 0.14) remained independent predictors of early age of crack-cocaine initiation.

CONCLUSIONS

Early onset of crack-cocaine use seems to be associated with exposure to family conflict, easy access to drugs and deviant behavior. Treatment and preventive programs should take these factors into account when designing and implementing community interventions.

摘要

背景

快克可卡因依赖是一个严重的公共卫生问题,与几种精神和社会心理问题有关。快克可卡因使用者通常处于高度社会脆弱的环境中,经常与暴力、贫困、家庭冲突以及容易和早期接触酒精、烟草和其他药物有关。

方法

这项横断面研究纳入了 2012 年 9 月至 2013 年 9 月期间在巴西南部的 20 个治疗社区连续收治的 577 名患者。通过结构化访谈评估了一生中接触药物使用风险和保护因素的情况,例如童年时期的父母监管、偏差行为和同伴压力。

结果

家庭冲突(p=0.002)、虐待(p=0.016)以及 15 岁前的偏差行为在双变量分析中预测了快克可卡因使用的较早年龄,而在青春期经历父母监管的青少年开始使用的年龄较晚(p<0.001)。在多变量模型中,与非法药物获取的便利性相关的认知(大麻:p=0.028,95%CI=-3.81,-0.22;快克可卡因:p<0.001,95%CI=-7.40,-4.90)以及偏差行为(用枪威胁某人:p=0.028,95%CI=-2.57,-0.14)仍然是快克可卡因使用早发的独立预测因素。

结论

快克可卡因使用的早期发病似乎与家庭冲突、容易获得毒品和偏差行为有关。治疗和预防计划在设计和实施社区干预措施时应考虑这些因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502b/8063477/a3552d810f9d/12889_2021_10769_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验