Narvaez Joana C M, Jansen Karen, Pinheiro Ricardo T, Kapczinski Flávio, Silva Ricardo A, Pechansky Flávio, Magalhães Pedro V S
Laboratório de Psiquiatria Molecular, National Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-003, Brazil,
Soc Psychiatry Psychiatr Epidemiol. 2014 Aug;49(8):1249-55. doi: 10.1007/s00127-014-0830-3. Epub 2014 Feb 12.
To estimate the prevalence of lifetime use of crack cocaine and to assess associations with violent and sexual behaviors in young adults selected from the general population of Pelotas, Southern Brazil.
This cross-sectional population-based study included 1,560 participants aged 18-24 years. The use of alcohol and other substances, including crack cocaine, was assessed using the alcohol, smoking and substance involvement screening test. Other variables included violent behaviors, firearm possession, and sexual risk behaviors. The frequency of antisocial personality disorder was also investigated. Associations were analyzed using a crude model and models adjusted for sex, social class, and the use of snorted cocaine.
Lifetime prevalence of crack cocaine use was 2.51 %, and it was higher among males and individuals coming from more vulnerable social classes (D or E). In the final multivariate models, lifetime use of crack cocaine was associated with episodes of aggression and firearm possession, as well as with a higher chance of not having used condom in the last sexual intercourse. In less conservative models, crack cocaine use was associated with other violent and sexual risk behaviors.
The strong association observed between lifetime use of crack cocaine and different violent and sexual risk behaviors underscores relevant characteristics of people who use crack cocaine. Improving our understanding of possible causal chains leading to such associations should be a priority in future studies.
评估巴西南部佩洛塔斯市普通人群中年轻成年人终生使用快克可卡因的患病率,并评估其与暴力行为和性行为之间的关联。
这项基于人群的横断面研究纳入了1560名年龄在18 - 24岁之间的参与者。使用酒精、吸烟和物质使用情况筛查测试来评估酒精及包括快克可卡因在内的其他物质的使用情况。其他变量包括暴力行为、持有枪支以及性风险行为。还调查了反社会人格障碍的发生频率。使用粗模型以及对性别、社会阶层和吸食可卡因情况进行调整后的模型来分析关联。
终生使用快克可卡因的患病率为2.51%,在男性以及来自更弱势社会阶层(D或E)的个体中更高。在最终的多变量模型中,终生使用快克可卡因与攻击行为发作、持有枪支以及在最近一次性交中未使用避孕套的较高可能性相关。在不太保守的模型中,使用快克可卡因与其他暴力和性风险行为相关。
终生使用快克可卡因与不同的暴力和性风险行为之间观察到的强烈关联突出了使用快克可卡因人群的相关特征。在未来研究中,优先提高我们对导致此类关联的可能因果链的理解。