Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada; Department of Biochemistry and Functional Genomics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Research Center on Aging, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Trends Genet. 2021 Aug;37(8):695-698. doi: 10.1016/j.tig.2021.03.010. Epub 2021 Apr 21.
Like protein-coding genes, long noncoding RNA (lncRNA) genes are composed of introns and exons. After their transcription, lncRNAs are subject to constitutive and/or alternative splicing. Here, we describe the current knowledge on lncRNA splice variants and their functional implications in cell biology.
与蛋白编码基因类似，长链非编码 RNA（lncRNA）基因也由内含子和外显子组成。lncRNA 在转录后，会经历组成性和/或选择性剪接。在这里，我们描述了 lncRNA 剪接变体的现有知识及其在细胞生物学中的功能意义。
