Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rue Henri Le Guilloux, 35033, Rennes, France.
Virology, Pontchaillou University Hospital, Rennes, France.
Eur J Clin Microbiol Infect Dis. 2021 Nov;40(11):2421-2425. doi: 10.1007/s10096-021-04261-y. Epub 2021 Apr 23.
We performed a prospective cohort study of 311 outpatients with non-severe COVID-19 (187 women, median age 39 years). Of the 214 (68.8%) who completed the 6-week follow-up questionnaire, 115 (53.7%) had recovered. Others mostly reported dyspnea (n = 86, 40.2%), weight loss (n = 83, 38.8%), sleep disorders (n = 68, 31.8%), and anxiety (n = 56, 26.2%). Of those who developed ageusia and anosmia, these symptoms were still present at week 6 in, respectively, 11/111 (9.9%) and 19/114 (16.7%). Chest CT scan and lung function tests found no explanation in the most disabled patients (n = 23). This study confirms the high prevalence of persistent symptoms after non-severe COVID-19.
我们对 311 名非重症 COVID-19 门诊患者（187 名女性，中位年龄 39 岁）进行了前瞻性队列研究。在完成 6 周随访问卷的 214 名患者中（68.8%），115 名（53.7%）已康复。其他人主要报告呼吸困难（n=86，40.2%）、体重减轻（n=83，38.8%）、睡眠障碍（n=68，31.8%）和焦虑（n=56，26.2%）。味觉和嗅觉丧失的患者中，这些症状在第 6 周仍存在于 111 名中的 11 名（9.9%）和 114 名中的 19 名（16.7%）。胸部 CT 扫描和肺功能检查在最残疾的患者（n=23）中未发现任何解释。本研究证实了非重症 COVID-19 后持续存在症状的高患病率。
