Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Brozzi Rosella, Galobart Jaume, Pettenati Elisa, Revez Joana, Innocenti Matteo Lorenzo
EFSA J. 2021 Apr 19;19(4):e06524. doi: 10.2903/j.efsa.2021.6524. eCollection 2021 Apr.
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the additive consisting of DSM 32325 when used as technological additive (hygiene condition enhancer) in feed for all animal species. The product is intended for use in dry feeds at a minimum inclusion level of 1 × 10 colony forming unit (CFU)/kg complete feedingstuff. The bacterial species DSM 32325 is considered by EFSA to be eligible for the qualified presumption of safety approach. As the identity of the strain has been clearly established and it did not show acquired resistance to antibiotics of human and veterinary importance, the use of the strain in animal nutrition is considered safe for the target species, consumers and the environment. No conclusions can be drawn on the skin/eye irritancy or skin sensitisation potential of the product. Exposure of users by inhalation is likely and the product should be considered a respiratory sensitiser. The Panel is not in the position to conclude on the efficacy of DSM 32325 when used in animal nutrition as hygiene condition enhancer due to lack of data. DSM 32325 is compatible with diclazuril, decoquinate and halofuginone. The data provided do not allow to conclude on the compatibility of the additive with monensin sodium, salinomycin sodium, narasin, robenidine hydrochloride and maduramicin ammonium.
应欧盟委员会的要求，动物饲料添加剂及产品或物质专家小组（FEEDAP）被要求就DSM 32325用作所有动物饲料中的技术添加剂（卫生条件增强剂）时给出科学意见。该产品旨在用于干饲料，最低添加水平为每千克全价饲料1×10菌落形成单位（CFU）。欧洲食品安全局（EFSA）认为DSM 32325细菌符合有条件安全推定方法的要求。由于该菌株的身份已明确确定，且未显示对人和兽医重要的抗生素产生获得性耐药性，因此该菌株在动物营养中的使用被认为对目标物种、消费者和环境是安全的。关于该产品的皮肤/眼睛刺激性或皮肤致敏潜力无法得出结论。使用者通过吸入接触该产品的可能性较大，该产品应被视为呼吸道致敏原。由于缺乏数据，专家小组无法就DSM 32325用作动物营养中的卫生条件增强剂的功效得出结论。DSM 32325与地克珠利、癸氧喹酯和常山酮兼容。所提供的数据无法就该添加剂与莫能菌素钠、盐霉素钠、那拉菌素、盐酸氯苯胍和马杜霉素铵的兼容性得出结论。
