达托霉素对高度耐青霉素的草绿色链球菌引起的感染性心内膜炎的疗效。
Effectiveness of daptomycin against infective endocarditis caused by highly penicillin-resistant viridans group streptococci.
作者信息
Matsuo Takahiro, Mori Nobuyoshi, Sakurai Aki, Kanie Takayoshi, Mikami Yumiko, Uehara Yuki, Furukawa Keiichi
机构信息
Department of Infectious Diseases, St. Luke's International Hospital, Tokyo, Japan.
Department of Cardiology, St. Luke's International Hospital, Tokyo, Japan.
出版信息
IDCases. 2021 Apr 5;24:e01113. doi: 10.1016/j.idcr.2021.e01113. eCollection 2021.
Penicillin-resistant viridans group streptococci (VGS) infections are an emerging issue in infectious diseases. Here, we present a case of mitral valve infective endocarditis caused by highly penicillin-resistant VGS (minimum inhibitory concentration >4 μg/mL), which was successfully treated with daptomycin. Although the clinical efficacy of daptomycin has not been established, it can be an alternative for the treatment of highly resistant VGS endocarditis.
对青霉素耐药的草绿色链球菌（VGS）感染是传染病领域中一个新出现的问题。在此，我们报告一例由对青霉素高度耐药的VGS（最低抑菌浓度>4μg/mL）引起的二尖瓣感染性心内膜炎病例，该病例用达托霉素成功治愈。尽管达托霉素的临床疗效尚未得到确证，但它可作为治疗高度耐药VGS心内膜炎的一种替代药物。
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