• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

达托霉素对高度耐青霉素的草绿色链球菌引起的感染性心内膜炎的疗效。

Effectiveness of daptomycin against infective endocarditis caused by highly penicillin-resistant viridans group streptococci.

作者信息

Matsuo Takahiro, Mori Nobuyoshi, Sakurai Aki, Kanie Takayoshi, Mikami Yumiko, Uehara Yuki, Furukawa Keiichi

机构信息

Department of Infectious Diseases, St. Luke's International Hospital, Tokyo, Japan.

Department of Cardiology, St. Luke's International Hospital, Tokyo, Japan.

出版信息

IDCases. 2021 Apr 5;24:e01113. doi: 10.1016/j.idcr.2021.e01113. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01113
PMID:33898259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8055607/
Abstract

Penicillin-resistant viridans group streptococci (VGS) infections are an emerging issue in infectious diseases. Here, we present a case of mitral valve infective endocarditis caused by highly penicillin-resistant VGS (minimum inhibitory concentration >4 μg/mL), which was successfully treated with daptomycin. Although the clinical efficacy of daptomycin has not been established, it can be an alternative for the treatment of highly resistant VGS endocarditis.

摘要

对青霉素耐药的草绿色链球菌（VGS）感染是传染病领域中一个新出现的问题。在此，我们报告一例由对青霉素高度耐药的VGS（最低抑菌浓度>4μg/mL）引起的二尖瓣感染性心内膜炎病例，该病例用达托霉素成功治愈。尽管达托霉素的临床疗效尚未得到确证，但它可作为治疗高度耐药VGS心内膜炎的一种替代药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa63/8055607/8f9505e380b2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa63/8055607/05f7a4233ea4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa63/8055607/8f9505e380b2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa63/8055607/05f7a4233ea4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa63/8055607/8f9505e380b2/gr2.jpg

相似文献

1
Effectiveness of daptomycin against infective endocarditis caused by highly penicillin-resistant viridans group streptococci.达托霉素对高度耐青霉素的草绿色链球菌引起的感染性心内膜炎的疗效。
IDCases. 2021 Apr 5;24:e01113. doi: 10.1016/j.idcr.2021.e01113. eCollection 2021.
2
Endocarditis Caused by Highly Penicillin-Resistant Viridans Group Streptococci: Still Room for Vancomycin-Based Regimens.由高度耐青霉素的草绿色链球菌引起的心内膜炎：万古霉素为基础的治疗方案仍有一席之地。
Antimicrob Agents Chemother. 2019 Jul 25;63(8). doi: 10.1128/AAC.00516-19. Print 2019 Aug.
3
Impact of Intermediate Susceptibility to Penicillin on Antimicrobial Treatment and Outcomes of Endocarditis Caused by Viridans and Gallolyticus Group Streptococci.青霉素中介度敏感性对导致心内膜炎的草绿色链球菌和缓症链球菌属的抗菌治疗和结局的影响。
Clin Infect Dis. 2023 Nov 11;77(9):1273-1281. doi: 10.1093/cid/ciad375.
4
Infective endocarditis caused by penicillin-resistant viridans group streptococci: a series of nine cases from a Spanish cohort.由耐青霉素的草绿色链球菌引起的感染性心内膜炎：来自西班牙队列的9例病例系列
J Antimicrob Chemother. 2024 Dec 2;79(12):3230-3235. doi: 10.1093/jac/dkae345.
5
In vitro activity of daptomycin against clinical isolates of Gram-positive bacteria.达托霉素对革兰氏阳性菌临床分离株的体外活性。
J Infect Chemother. 2005 Aug;11(4):207-9. doi: 10.1007/s10156-005-0395-x.
6
Daptomycin tested against 915 bloodstream isolates of viridans group streptococci (eight species) and Streptococcus bovis.对915株草绿色链球菌（8个种）和牛链球菌血流分离株进行了达托霉素检测。
J Antimicrob Chemother. 2005 Apr;55(4):574-8. doi: 10.1093/jac/dki032. Epub 2005 Feb 18.
7
Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci.牙周治疗联合阿莫西林-甲硝唑对青霉素和红霉素耐药草绿色链球菌咽部携带的影响。
J Periodontol. 2016 May;87(5):539-47. doi: 10.1902/jop.2015.150494. Epub 2015 Dec 14.
8
Penicillin therapy for treatment of experimental endocarditis caused by viridans streptococci in animals.青霉素疗法用于治疗动物由草绿色链球菌引起的实验性心内膜炎。
J Infect Dis. 1985 Jun;151(6):1028-33. doi: 10.1093/infdis/151.6.1028.
9
Species-specific difference in antimicrobial susceptibility among viridans group streptococci.草绿色链球菌群中不同种属间的抗菌药物敏感性差异。
Ann Lab Med. 2015 Mar;35(2):205-11. doi: 10.3343/alm.2015.35.2.205. Epub 2015 Feb 12.
10
Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci.与草绿色链球菌相比，导致阿比奥特罗和颗粒链球菌感染性心内膜炎的临床特征和结局。
J Infect. 2022 Aug;85(2):137-146. doi: 10.1016/j.jinf.2022.05.023. Epub 2022 May 23.

引用本文的文献

1
Glucose Supplementation Enhances the Bactericidal Effect of Penicillin and Gentamicin on Persisters.补充葡萄糖可增强青霉素和庆大霉素对持留菌的杀菌作用。
Antibiotics (Basel). 2025 Jan 5;14(1):36. doi: 10.3390/antibiotics14010036.
2
Breeding of High Daptomycin-Producing Strain by Streptomycin Resistance Superposition.通过链霉素抗性叠加培育高产达托霉素菌株。
Pol J Microbiol. 2022 Sep 24;71(3):463-471. doi: 10.33073/pjm-2022-041. eCollection 2022 Sep 1.

本文引用的文献

1
Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association.成人感染性心内膜炎：诊断、抗菌治疗和并发症处理：美国心脏协会医疗保健专业人员科学声明。
Circulation. 2015 Oct 13;132(15):1435-86. doi: 10.1161/CIR.0000000000000296. Epub 2015 Sep 15.
2
2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).2015年欧洲心脏病学会（ESC）感染性心内膜炎管理指南：欧洲心脏病学会（ESC）感染性心内膜炎管理工作组。认可机构：欧洲心胸外科学会（EACTS）、欧洲核医学协会（EANM）。
Eur Heart J. 2015 Nov 21;36(44):3075-3128. doi: 10.1093/eurheartj/ehv319. Epub 2015 Aug 29.
3
High-dose daptomycin therapy for left-sided infective endocarditis: a prospective study from the international collaboration on endocarditis.高剂量达托霉素治疗左心感染性心内膜炎：国际心内膜炎协作组的前瞻性研究。
Antimicrob Agents Chemother. 2013 Dec;57(12):6213-22. doi: 10.1128/AAC.01563-13. Epub 2013 Sep 30.
4
A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis.高剂量达托霉素治疗感染性心内膜炎有效性和安全性的多中心评估
J Antimicrob Chemother. 2013 Dec;68(12):2921-6. doi: 10.1093/jac/dkt294. Epub 2013 Aug 8.
5
Penicillin G-resistant viridans group streptococcal endocarditis and interpretation of the American Heart Association's Guidelines for the Treatment of Infective Endocarditis.耐青霉素G的草绿色链球菌心内膜炎及美国心脏协会感染性心内膜炎治疗指南解读
Clin Infect Dis. 2008 Apr 1;46(7):1064-6. doi: 10.1086/529199.
6
Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.达托霉素与标准疗法治疗金黄色葡萄球菌引起的菌血症和心内膜炎的比较。
N Engl J Med. 2006 Aug 17;355(7):653-65. doi: 10.1056/NEJMoa053783.
7
Guidelines for the antibiotic treatment of endocarditis in adults: report of the Working Party of the British Society for Antimicrobial Chemotherapy.成人感染性心内膜炎抗生素治疗指南：英国抗菌化疗协会工作组报告
J Antimicrob Chemother. 2004 Dec;54(6):971-81. doi: 10.1093/jac/dkh474. Epub 2004 Nov 16.
8
Antimicrobial susceptibility patterns among viridans group streptococcal isolates from infective endocarditis patients from 1971 to 1986 and 1994 to 2002.1971年至1986年以及1994年至2002年期间感染性心内膜炎患者的草绿色链球菌分离株的抗菌药敏模式。
Antimicrob Agents Chemother. 2004 Nov;48(11):4463-5. doi: 10.1128/AAC.48.11.4463-4465.2004.
9
Viridans group streptococci: a reservoir of resistant bacteria in oral cavities.草绿色链球菌：口腔中耐药菌的储存库。
Clin Microbiol Infect. 2002 Feb;8(2):65-9. doi: 10.1046/j.1198-743x.2001.00398.x.
10
Infective endocarditis in adults.成人感染性心内膜炎
N Engl J Med. 2001 Nov 1;345(18):1318-30. doi: 10.1056/NEJMra010082.