囊性纤维化的家庭静脉抗生素治疗。
Home intravenous antibiotic treatment in cystic fibrosis.
作者信息
Gilbert J, Robinson T, Littlewood J M
机构信息
Regional Cystic Fibrosis Unit, St James's University Hospital, Leeds.
出版信息
Arch Dis Child. 1988 May;63(5):512-7. doi: 10.1136/adc.63.5.512.
The prognosis for patients with cystic fibrosis who are colonised with Pseudomonas aeruginosa has improved as a result of the regular use of intravenous antibiotics; however, this necessitates long periods of hospitalisation. Home intravenous antibiotic treatment has potential advantages over hospital treatment. We describe our experience during the first 20 months of using a system of home intravenous antibiotic treatment in which a cystic fibrosis liaison sister has an essential role. Thirteen patients have received 40 courses of treatment. There were highly significant improvements in weight, respiratory function, and white cell count during home treatment. There was no significant difference in weight and forced expiratory volume in one second between the end of home treatment and the end of hospital treatment while forced vital capacity was better after home treatment. All patients preferred home treatment. The advantages of home visits by the cystic fibrosis liaison sister during treatment are emphasised.
由于定期使用静脉抗生素，囊性纤维化合并铜绿假单胞菌感染患者的预后有所改善；然而，这需要长期住院。家庭静脉抗生素治疗相对于医院治疗具有潜在优势。我们描述了在使用家庭静脉抗生素治疗系统的前20个月中的经验，其中囊性纤维化联络护士发挥了重要作用。13名患者接受了40个疗程的治疗。在家治疗期间，体重、呼吸功能和白细胞计数有显著改善。在家治疗结束时与医院治疗结束时相比，体重和一秒用力呼气量没有显著差异，而用力肺活量在家治疗后更好。所有患者都更喜欢在家治疗。强调了囊性纤维化联络护士在治疗期间进行家访的优势。
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