Bothe A, Piccione W, Ambrosino J J, Benotti P N, Lokich J J
Am J Surg. 1984 Apr;147(4):565-9. doi: 10.1016/0002-9610(84)90023-0.
Prolonged central venous access for outpatient chemotherapy was achieved in 74 patients utilizing a totally implantable access disc system. The system consists of a stainless steel drug reservoir implanted in the subcutaneous tissue of the anterior chest wall. The reservoir is attached to a Silastic catheter which is then tunneled to a central vein and positioned in the superior vena cava. In 6,762 patient days of observation, there was a high degree of patient acceptance and a low incidence of complications. There were four instances of thrombosis and two of catheter-related sepsis among 17 complications. Seven access discs required removal. The implantable nature of this system offers an attractive alternative to other available methods of prolonged central venous access.
74例患者采用完全植入式接入盘系统实现了门诊化疗的长期中心静脉通路。该系统由一个植入前胸壁皮下组织的不锈钢药物储存器组成。储存器连接到一个硅胶导管，然后通过隧道连接到中心静脉并置于上腔静脉。在6762个患者观察日中，患者接受度高，并发症发生率低。17例并发症中有4例血栓形成，2例导管相关败血症。7个接入盘需要取出。该系统的可植入特性为其他现有的长期中心静脉通路方法提供了一个有吸引力的替代方案。
