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Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2021 Feb 25;38(1):161-168. doi: 10.7507/1001-5515.202002029.
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First patients treated with a 1.5 T MRI-Linac: clinical proof of concept of a high-precision, high-field MRI guided radiotherapy treatment.首例接受1.5T磁共振直线加速器治疗的患者:高精度、高场强磁共振引导放射治疗的临床概念验证。
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本文引用的文献

1
Magnetic resonance-guided radiation therapy: A review.磁共振引导放射治疗:综述。
J Med Imaging Radiat Oncol. 2020 Feb;64(1):163-177. doi: 10.1111/1754-9485.12968. Epub 2019 Oct 23.
2
MRIgRT dynamic lung motion thorax anthropomorphic QA phantom: Design, development, reproducibility, and feasibility study.MRIgRT 动态肺运动胸部人体模体:设计、开发、可重复性和可行性研究。
Med Phys. 2019 Nov;46(11):5124-5133. doi: 10.1002/mp.13757. Epub 2019 Sep 11.
3
A novel transport sweep architecture for efficient deterministic patient dose calculations in MRI-guided radiotherapy.一种新型传输扫描架构,可提高 MRI 引导放疗中高效确定性患者剂量计算的效率。
Phys Med Biol. 2019 Sep 19;64(18):185012. doi: 10.1088/1361-6560/ab35bc.
4
Adaptive radiotherapy: The Elekta Unity MR-linac concept.自适应放疗:医科达Unity MR直线加速器概念
Clin Transl Radiat Oncol. 2019 Apr 2;18:54-59. doi: 10.1016/j.ctro.2019.04.001. eCollection 2019 Sep.
5
First clinical experiences with a high field 1.5 T MR linac.首例高场 1.5TMR 直线加速器的临床应用经验
Acta Oncol. 2019 Oct;58(10):1352-1357. doi: 10.1080/0284186X.2019.1627417. Epub 2019 Jun 26.
6
A new frontier of image guidance: Organs at risk avoidance with MRI-guided respiratory-gated intensity modulated radiotherapy: Technical note and report of a case.图像引导的新前沿:MRI 引导呼吸门控调强放疗中规避危险器官:技术说明和病例报告。
J Appl Clin Med Phys. 2019 Jun;20(6):194-198. doi: 10.1002/acm2.12575. Epub 2019 May 4.
7
Online adaptive magnetic resonance guided radiotherapy for pancreatic cancer: state of the art, pearls and pitfalls.在线自适应磁共振引导胰腺癌放疗:现状、要点和陷阱。
Radiat Oncol. 2019 Apr 29;14(1):71. doi: 10.1186/s13014-019-1275-3.
8
Technical Note: The first live treatment on a 1.0 Tesla inline MRI-linac.技术说明:在 1.0 特斯拉直线型磁共振加速器上进行的首次现场治疗。
Med Phys. 2019 Jul;46(7):3254-3258. doi: 10.1002/mp.13556. Epub 2019 May 10.
9
Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Diagnostic Tool in the Assessment of Tumour Angiogenesis in Urinary Bladder Cancer.动态对比增强磁共振成像作为膀胱癌肿瘤血管生成评估的诊断工具。
Can Assoc Radiol J. 2019 Aug;70(3):254-263. doi: 10.1016/j.carj.2018.11.004. Epub 2019 Mar 25.
10
Preoperative Diffusion Tensor Imaging: A Landmark Modality for Predicting the Outcome and Characterization of Supratentorial Intra-Axial Brain Tumors.术前弥散张量成像:预测幕上脑实质内肿瘤预后及特征的标志性检查手段
World Neurosurg. 2019 Apr;124:e540-e551. doi: 10.1016/j.wneu.2018.12.146. Epub 2019 Jan 10.

[磁共振成像引导放射治疗的进展]

[Advances in magnetic resonance imaging guided radiation therapy].

作者信息

Xu Wenzhe, Wang Changjian, Ma Yiming, Fang Chunfeng, Gong Hanshun, Zhang Gaolong, Qu Baolin, Xu Shouping

机构信息

School of Physics, Beihang University, Beijing 100191, P. R.China;Department of Radiotherapy, PLA General Hospital, Beijing 100853, P. R. China.

Department of Radiotherapy, Yizhou Tumor Hospital, Zhuozhou, Hebei 072750, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2021 Feb 25;38(1):161-168. doi: 10.7507/1001-5515.202002029.

DOI:10.7507/1001-5515.202002029
PMID:33899441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10307565/
Abstract

Image-guided radiation therapy using magnetic resonance imaging (MRI) is a new technology that has been widely studied and developed in recent years. The technology combines the advantages of MRI imaging, and can offer online real-time tracking of tumor and adjacent organs at risk, as well as real-time optimization of radiotherapy plan. In order to provide a comprehensive understanding of this technology, and to grasp the international development and trends in this field, this paper reviews and summarizes related researches, so as to make the researchers and clinical personnel in this field to understand recent status of this technology, and carry out corresponding researches. This paper summarizes the advantages of MRI and the research progress of MRI linear accelerator (MR-Linac), online guidance, adaptive optimization, and dosimetry-related research. Possible development direction of these technologies in the future is also discussed. It is expected that this review can provide a certain reference value for clinician and related researchers to understand the research progress in the field.

摘要

使用磁共振成像(MRI)的图像引导放射治疗是近年来得到广泛研究和发展的一项新技术。该技术结合了MRI成像的优势,能够对肿瘤及邻近危险器官进行在线实时追踪,以及对放射治疗计划进行实时优化。为了全面了解这项技术,并把握该领域的国际发展情况及趋势,本文对相关研究进行综述和总结,以便该领域的研究人员和临床人员了解该技术的最新状况,并开展相应研究。本文总结了MRI的优势以及MRI直线加速器(MR-Linac)、在线引导、自适应优化和剂量学相关研究的进展情况。还讨论了这些技术未来可能的发展方向。期望本综述能为临床医生和相关研究人员了解该领域的研究进展提供一定的参考价值。