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基于卷积神经网络的乳腺超声图像分类方法,采用 mRMR 混合方法对良性、恶性和正常进行分类。

Convolutional Neural Networks based classification of breast ultrasonography images by hybrid method with respect to benign, malignant, and normal using mRMR.

机构信息

Department of Radiology, Firat University School of Medicine, Elazig, Turkey.

Computer Engineering Department, Firat University, Elazig, Turkey.

出版信息

Comput Biol Med. 2021 Jun;133:104407. doi: 10.1016/j.compbiomed.2021.104407. Epub 2021 Apr 19.

Abstract

Early diagnosis of breast lesions and differentiation of malignant lesions from benign lesions are important for the prognosis of breast cancer. In the diagnosis of this disease ultrasound is an extremely important radiological imaging method because it enables biopsy as well as lesion characterization. Since ultrasonographic diagnosis depends on the expert, the knowledge level and experience of the user is very important. In addition, the contribution of computer aided systems is quite high, as these systems can reduce the workload of radiologists and reinforce their knowledge and experience when considered together with a dense patient population in hospital conditions. In this paper, a hybrid based CNN system is developed for diagnosing breast cancer lesions with respect to benign, malignant and normal. Alexnet, MobilenetV2, and Resnet50 models are used as the base for the Hybrid structure. The features of these models used are obtained and concatenated separately. Thus, the number of features used are increased. Later, the most valuable of these features are selected by the mRMR (Minimum Redundancy Maximum Relevance) feature selection method and classified with machine learning classifiers such as SVM, KNN. The highest rate is obtained in the SVM classifier with 95.6% in accuracy.

摘要

早期诊断乳腺病变,区分良恶性病变,对乳腺癌的预后具有重要意义。在这种疾病的诊断中,超声是一种极其重要的影像学方法,因为它可以进行活检和病变特征分析。由于超声诊断依赖于专家,因此用户的知识水平和经验非常重要。此外,计算机辅助系统的贡献也相当高,因为这些系统可以减轻放射科医生的工作量,并在考虑到医院条件下的大量患者时,增强他们的知识和经验。在本文中,开发了一种基于混合 CNN 的系统,用于诊断乳腺良、恶性和正常病变。Alexnet、MobilenetV2 和 Resnet50 模型被用作混合结构的基础。分别获取和连接这些模型的特征。因此,使用的特征数量增加了。然后,通过最小冗余最大相关性 (mRMR) 特征选择方法选择这些特征中最有价值的特征,并使用机器学习分类器(如 SVM、KNN)进行分类。在 SVM 分类器中获得了最高的准确率 95.6%。

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