Lv Xing, Yuan Mengting, Pei Yuehong, Liu Changyun, Wang Xiangchuan, Wu Lei, Cheng Daoquan, Ma Xiaozhou, Sun Xianchao
College of Plant Protection, Southwest University, Chongqing 400715, China.
Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing, Southwest University, Chongqing 400715, China.
J Agric Food Chem. 2021 May 5;69(17):4992-5002. doi: 10.1021/acs.jafc.1c00941. Epub 2021 Apr 27.
Improving the efficiency and prolonging the duration of pesticides are of great significance in agricultural production. In this work, based on the antiviral compound chloroinconazide (CHI) synthesized previously, the improvement of the fabricated CHI-loaded alginate-based nanogel (CHI@ALGNP) was studied. It was found that CHI@ALGNP showed higher foliar adhesion than CHI and exhibited a sustained release for up to 7 days. CHI@ALGNP could also continuously activate the reactive oxygen species and antioxidant levels and induce the increase of salicylic acid content and the expression of its responsive gene for a long time, thus achieving sustained resistance to tobacco mosaic virus infection in . Strikingly, CHI@ALGNP could release Ca and Mg to promote the growth of . Taken together, for the first time, we have shown the improvement of a nanogel carrier to the antiviral activity and growth promotion of small molecular pesticides. As the alginate-based nanogel can be easily applied to the spray-based pesticide delivery technology, our study provides a new strategy for the development of new pesticide preparations and the application of multifunctional pesticides.
提高农药的效率和延长其持效期在农业生产中具有重要意义。在这项工作中，基于先前合成的抗病毒化合物氯吲哚菌酯（CHI），研究了制备的负载CHI的海藻酸盐基纳米凝胶（CHI@ALGNP）的改进情况。结果发现，CHI@ALGNP比CHI表现出更高的叶面附着力，并呈现出长达7天的缓释效果。CHI@ALGNP还能持续激活活性氧和抗氧化水平，并长期诱导水杨酸含量增加及其响应基因的表达，从而在烟草中实现对烟草花叶病毒感染的持续抗性。引人注目的是，CHI@ALGNP可以释放钙和镁以促进烟草生长。综上所述，我们首次展示了纳米凝胶载体对小分子农药抗病毒活性和生长促进作用的改善。由于海藻酸盐基纳米凝胶可以很容易地应用于喷雾型农药递送技术，我们的研究为新型农药制剂的开发和多功能农药的应用提供了一种新策略。
