California Maternal Quality Care Collaborative, Stanford University, Stanford.
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco.
JAMA. 2021 Apr 27;325(16):1631-1639. doi: 10.1001/jama.2021.3816.
Safe reduction of the cesarean delivery rate is a national priority.
To evaluate the rates of cesarean delivery for nulliparous, term, singleton, vertex (NTSV) births in California in the context of a statewide multifaceted intervention designed to reduce the rates of cesarean delivery.
DESIGN, SETTING, AND PARTICIPANTS: Observational study of cesarean delivery rates from 2014 to 2019 among 7 574 889 NTSV births in the US and at 238 nonmilitary hospitals providing maternity services in California. From 2016 to 2019, California Maternal Quality Care Collaborative partnered with Smart Care California to implement multiple approaches to decrease the rates of cesarean delivery. Hospitals with rates of cesarean delivery greater than 23.9% for NTSV births were invited to join 1 of 3 cohorts for an 18-month quality improvement collaborative between July 2016 and June 2019.
Within the collaborative, multidisciplinary teams implemented multiple strategies supported by mentorship, shared learning, and rapid-cycle data feedback. Partnerships among nonprofit organizations, state governmental agencies, purchasers, and health plans addressed the external environment through transparency, award programs, and incentives.
The primary outcome was the change in cesarean delivery rates for NTSV births in California and a difference-in-differences analysis was performed to compare cesarean delivery rates for NTSV births in California vs the rates in the rest of the US. A mixed multivariable logistic regression model that adjusted for patient-level and hospital-level confounders also was used to assess the collaborative and the external statewide actions. The cesarean delivery rates for NTSV births at hospitals participating in the collaborative were compared with the rates from the nonparticipating hospitals and the rates in the participating hospitals prior to participation in the collaborative.
A total of 7 574 889 NTSV births occurred in the US from 2014 to 2019, of which 914 283 were at 238 hospitals in California. All California hospitals were exposed to the statewide actions to reduce the rates of cesarean delivery, including the 149 hospitals that had baseline rates of cesarean delivery greater than 23.9% for NTSV births, of which 91 (61%) participated in the quality improvement collaborative. The rate of cesarean delivery for NTSV births in California decreased from 26.0% (95% CI, 25.8%-26.2%) in 2014 to 22.8% (95% CI, 22.6%-23.1%) in 2019 (relative risk, 0.88; 95% CI, 0.87-0.89). The rate of cesarean delivery for NTSV births in the US (excluding California births) was 26.0% in both 2014 and 2019 (relative risk, 1.00; 95% CI, 0.996-1.005). The difference-in-differences analysis revealed that the reduction in the rate of cesarean delivery for NTSV births in California was 3.2% (95% CI, 1.7%-3.5%) higher than in the US (excluding California). Compared with the hospitals and the periods not exposed to the collaborative activities, and after adjusting for patient characteristics and time using a modified stepped-wedge analysis, exposure to collaborative activities was associated with a lower odds of cesarean delivery for NTSV births (24.4% vs 24.6%; adjusted odds ratio, 0.87 [95% CI, 0.85-0.89]).
In this observational study of NTSV births in California from 2014 to 2019, the rates of cesarean delivery decreased over time in the setting of the implementation of a coordinated hospital-level collaborative and statewide initiatives designed to support vaginal birth.
重要性:安全降低剖宫产率是国家的当务之急。
目的:评估加利福尼亚州在一项旨在降低剖宫产率的全州多方面干预措施背景下,初产妇、足月、单胎、头位(NTSV)分娩的剖宫产率。
设计、地点和参与者:这是一项观察性研究,对 2014 年至 2019 年期间美国 7574889 例 NTSV 分娩和加利福尼亚州 238 家提供产妇服务的非军事医院的剖宫产率进行了研究。从 2016 年至 2019 年,加利福尼亚州产妇质量护理协作组织与 Smart Care California 合作,实施了多种方法来降低剖宫产率。对于 NTSV 分娩的剖宫产率超过 23.9%的医院,邀请他们参加为期 18 个月的质量改进合作,该合作于 2016 年 7 月至 2019 年 6 月进行。
暴露:在协作过程中,多学科团队实施了多种策略,这些策略得到了指导、共享学习和快速循环数据反馈的支持。非营利组织、州政府机构、购买者和健康计划之间的伙伴关系通过透明度、奖励计划和激励措施来解决外部环境问题。
主要结果和措施:主要结果是加利福尼亚州 NTSV 分娩的剖宫产率的变化,并且进行了差异分析,以比较加利福尼亚州 NTSV 分娩的剖宫产率与美国其他地区的剖宫产率。还使用了调整患者水平和医院水平混杂因素的混合多变量逻辑回归模型来评估协作和全州范围的行动。与未参与协作的医院相比,参与协作的医院和参与协作前的医院的 NTSV 分娩剖宫产率进行了比较。
结果:2014 年至 2019 年,美国共有 7574889 例 NTSV 分娩,其中 238 家医院位于加利福尼亚州。所有加利福尼亚州的医院都接触到了降低剖宫产率的全州行动,包括基线 NTSV 分娩剖宫产率超过 23.9%的 149 家医院,其中 91 家(61%)参与了质量改进合作。加利福尼亚州 NTSV 分娩的剖宫产率从 2014 年的 26.0%(95%CI,25.8%-26.2%)降至 2019 年的 22.8%(95%CI,22.6%-23.1%)(相对风险,0.88;95%CI,0.87-0.89)。美国(不包括加利福尼亚州的分娩)的 NTSV 分娩剖宫产率在 2014 年和 2019 年均为 26.0%(相对风险,1.00;95%CI,0.996-1.005)。差异分析显示,加利福尼亚州 NTSV 分娩的剖宫产率下降了 3.2%(95%CI,1.7%-3.5%),高于美国(不包括加利福尼亚州)。与未接触合作活动的医院和时期相比,并且在使用修正的逐步楔形分析调整患者特征和时间后,暴露于合作活动与 NTSV 分娩的剖宫产率较低相关(24.4%比 24.6%;调整后的优势比,0.87 [95%CI,0.85-0.89])。
结论和相关性:在 2014 年至 2019 年期间对加利福尼亚州 NTSV 分娩的这项观察性研究中,在实施协调医院级合作和全州倡议以支持阴道分娩的背景下,剖宫产率随着时间的推移而下降。