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唐氏综合征与自闭症谱系障碍共病:认知、适应及行为特征

Co-occurring Down Syndrome and Autism Spectrum Disorder: Cognitive, Adaptive, and Behavioral Characteristics.

作者信息

Bradbury Kathryn R, Anderberg Emily I, Huang-Storms Lark, Vasile Iulia, Greene Rachel K, Duvall Susanne W

机构信息

Division of Pediatric Psychology, Department of Pediatrics, Institute on Development and Disability, Oregon Health & Science University and Doernbecher Children's Hospital, Portland, OR, USA.

Children's Neuropsychological Services, Andover, MA, USA.

出版信息

J Autism Dev Disord. 2022 Mar;52(3):1235-1246. doi: 10.1007/s10803-021-05016-6. Epub 2021 Apr 27.

Abstract

The current study explores functioning in individuals with co-occurring Autism Spectrum Disorder and Down Syndrome (ASD+DS; n = 23), individuals with ASD and cognitive impairment (ASD+ID; n = 99) and individuals with idiopathic ID (n = 38). ANCOVA results revealed that individuals with ASD+DS showed strengths in behavioral functioning compared to individuals with ID and more similar behavioral functioning to those with ASD+ID (η = 0.12), with the exception of disruptive behaviors. Cognitive functioning (ɸ = 0.41) and ASD symptomatology (η = 0.11) were more comparable for children with ASD+DS and ASD + ID than for individuals with ID. Individuals with ASD+DS had the lowest overall adaptive skills (η = 0.11). Findings highlight similarities between ASD+DS and ASD+ID groups, emphasizing the importance of ASD identification within the DS population to provide access to specific interventions.

摘要

本研究探讨了同时患有自闭症谱系障碍和唐氏综合征(ASD+DS;n = 23)的个体、患有自闭症和认知障碍(ASD+ID;n = 99)的个体以及患有特发性智力障碍(n = 38)的个体的功能情况。协方差分析结果显示,与智力障碍个体相比,ASD+DS个体在行为功能方面表现出优势,并且在行为功能上与ASD+ID个体更为相似(η = 0.12),但破坏性行为除外。ASD+DS儿童和ASD+ID儿童在认知功能(ɸ = 0.41)和自闭症症状(η = 0.11)方面比智力障碍个体更具可比性。ASD+DS个体的总体适应技能最低(η = 0.11)。研究结果突出了ASD+DS组和ASD+ID组之间的相似性,强调了在唐氏综合征人群中识别自闭症以提供特定干预措施的重要性。

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