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运动认知风险的流行率/潜在危险因素及其与老年人跌倒的关系:一项横断面研究。

Prevalence/potential risk factors for motoric cognitive risk and its relationship to falls in elderly Chinese people: a cross-sectional study.

机构信息

Department of Neurology, Beijing Daxing District People's Hospital, Beijing, China.

Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

出版信息

Eur J Neurol. 2021 Aug;28(8):2680-2687. doi: 10.1111/ene.14884. Epub 2021 May 14.

Abstract

BACKGROUND AND PURPOSE

Motoric cognitive risk syndrome (MCR) is characterized by slow walking speed and subjective memory complaints (SMCs). This study investigated the prevalence and potential risk factors of MCR and its association with falls in Chinese community-dwelling older adults.

METHODS

The analysis was based on data from the Rugao Longevity and Aging Study (RuLAS). MCR was defined as the presence of both SMCs and slow walking speed in participants free of major neurocognitive disorders. SMCs were determined according to a positive answer to the question 'Do you feel you have more problems with memory than most?' in the 15-item Geriatric Depression Scale. Slow walking speed was defined as one standard deviation or more below the mean value for patients' age and sex. Data on falls were derived from a standardized questionnaire.

RESULTS

The prevalence of SMCs, slow walking speed and MCR in the RuLAS cohort (N = 1592) was 51.9%, 15.6% and 8.3%, respectively. After adjusting for other covariates, an occupation of farming (odds ratio [OR] 2.358, 95% confidence interval [CI] 1.007-5.521, p = 0.048), history of cerebrovascular disease (OR 2.215, 95% CI 1.032-4.752, p = 0.041) and hospitalization (OR 2.008, 95% CI 1.120-3.602, p = 0.019) were risk factors for MCR. Binary logistic regression analysis indicated that the risk of falls was increased by MCR (OR 1.547, 95% CI 1.009-2.371), SMC (OR 1.308, 95% CI 1.003-1.707) and slow walking speed (OR 1.442, 95% CI 1.030-2.017).

CONCLUSIONS

Early identification of potential risk factors of MCR can prevent the occurrence of adverse health events such as falls in the elderly.

摘要

背景与目的

运动认知风险综合征(MCR)的特征是行走速度缓慢和存在主观记忆主诉(SMC)。本研究旨在调查运动认知风险综合征在我国社区居住的老年人中的流行情况及其潜在危险因素,并探讨其与跌倒之间的关系。

方法

本研究基于如皋长寿与衰老研究(RuLAS)的数据进行分析。MCR 的定义为:无重大神经认知障碍的参与者同时存在 SMC 和行走速度缓慢。SMC 通过老年抑郁量表的 15 项问题中“您是否觉得自己的记忆力比大多数人都差?”这一问题的肯定回答来确定。行走速度缓慢定义为患者年龄和性别均数的一个标准差或更多。跌倒数据来源于标准化问卷。

结果

在 RuLAS 队列中(N=1592),SMC、行走速度缓慢和 MCR 的发生率分别为 51.9%、15.6%和 8.3%。在校正其他混杂因素后,务农职业(比值比[OR] 2.358,95%置信区间[CI] 1.007-5.521,p=0.048)、脑血管病史(OR 2.215,95% CI 1.032-4.752,p=0.041)和住院史(OR 2.008,95% CI 1.120-3.602,p=0.019)是 MCR 的危险因素。二项逻辑回归分析表明,MCR(OR 1.547,95% CI 1.009-2.371)、SMC(OR 1.308,95% CI 1.003-1.707)和行走速度缓慢(OR 1.442,95% CI 1.030-2.017)均会增加跌倒的风险。

结论

早期识别 MCR 的潜在危险因素可以预防老年人发生跌倒等不良健康事件。

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