Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan.
Sci Rep. 2021 Apr 27;11(1):9088. doi: 10.1038/s41598-021-88728-0.
The metabolically healthy obese (MHO) characterized by the absence of metabolic syndrome have shown superior cardiorespiratory fitness (CRF) and similar muscular strength as compared with the metabolically unhealthy obese (MUO). However, this finding might be biased by the baseline sedentary behavior in the general population. This study utilized 3669 physically active military males aged 18-50 years in Taiwan. Obesity and metabolically unhealthy were respectively defined as body mass index ≥ 27.5 kg/m and presence of at least two major components of the metabolic syndrome, according to the International Diabetes Federation criteria for Asian male adults. Four groups were accordingly classified as the metabolically healthy lean (MHL, n = 2510), metabolically unhealthy lean (MUL, n = 331), MHO (n = 181) and MUO (n = 647). CRF was evaluated by time for a 3-km run, and muscular strengths were separately assessed by numbers of push-up and sit-up within 2 min. Analysis of covariance was utilized to compare the difference in each exercise performance between groups adjusting for age, service specialty, smoking, alcohol intake and physical activity. The metabolic syndrome prevalence in MUL and MUO was 49.8% and 47.6%, respectively. The performance of CRF did not differ between MHO and MUO (892.3 ± 5.4 s and 892.6 ± 3.0 s, p = 0.97) which were both inferior to MUL and MHL (875.2 ± 4.0 s and 848.6 ± 1.3 s, all p values < 0.05). The performance of muscular strengths evaluated by 2-min push-ups did not differ between MUL and MUO (45.3 ± 0.6 and 45.2 ± 0.4, p = 0.78) which were both less than MHO and MHL (48.4 ± 0.8 and 50.6 ± 0.2, all p values < 0.05). However, the performance of 2-min sit-ups were only superior in MHL (48.1 ± 0.1) as compared with MUL, MHO and MUO (45.9 ± 0.4, 46.7 ± 0.5 and 46.1 ± 0.3, respectively, all p values < 0.05). Our findings suggested that in a physically active male cohort, the MHO might have greater muscle strengths, but have similar CRF level compared with the MUO.
代谢健康型肥胖（MHO）的特征是没有代谢综合征，与代谢不健康型肥胖（MUO）相比，他们表现出更好的心肺功能（CRF）和相似的肌肉力量。然而，这一发现可能会因普通人群的基线久坐行为而存在偏差。本研究利用了台湾 3669 名年龄在 18-50 岁之间的活跃军人男性。根据国际糖尿病联合会（International Diabetes Federation）针对亚洲成年男性的标准，肥胖和代谢不健康分别定义为体重指数≥27.5kg/m2和至少存在代谢综合征的两个主要成分。因此，根据这一标准将参与者分为四个组，分别为代谢健康的瘦人（MHL，n=2510）、代谢不健康的瘦人（MUL，n=331）、MHO（n=181）和 MUO（n=647）。CRF 通过 3 公里跑的时间来评估，肌肉力量分别通过 2 分钟内的俯卧撑和仰卧起坐次数来评估。使用协方差分析比较各组之间在调整年龄、服务专业、吸烟、饮酒和身体活动后每个运动表现的差异。MUL 和 MUO 中的代谢综合征患病率分别为 49.8%和 47.6%。MHO 和 MUO 的 CRF 表现无差异（892.3±5.4s 和 892.6±3.0s，p=0.97），均低于 MUL 和 MHL（875.2±4.0s 和 848.6±1.3s，所有 p 值均<0.05）。2 分钟俯卧撑评估的肌肉力量表现，MUL 和 MUO 之间无差异（45.3±0.6 和 45.2±0.4，p=0.78），均低于 MHO 和 MHL（48.4±0.8 和 50.6±0.2，所有 p 值均<0.05）。然而，2 分钟仰卧起坐的表现仅在 MHL 中更好（48.1±0.1），而在 MUL、MHO 和 MUO 中则更差（45.9±0.4、46.7±0.5 和 46.1±0.3，所有 p 值均<0.05）。我们的研究结果表明，在一个活跃的男性队列中，与 MUO 相比，MHO 可能具有更大的肌肉力量，但 CRF 水平相似。
