State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China.
Virol Sin. 2021 Dec;36(6):1261-1272. doi: 10.1007/s12250-021-00365-z. Epub 2021 Apr 28.
Porcine bocavirus (PBoV) is a single-stranded DNA virus, belongs to the genus Bocaparvovirus of family Parvoviridae. It was discovered along with porcine circovirus 2 (PCV 2) and torque tenovirus (TTV) in the lymph nodes of pigs suffering from postweaning multisystemic wasting syndrome (PMWS) in Sweden in 2009. PBoV has been reported throughout the world, mostly in weaning piglets, and has a broad range of tissue tropism. Since PBoV is prevalent in healthy as well as clinically infected pigs and is mostly associated with coinfection with other viruses, the pathogenic nature of PBoV is still unclear. Currently, there are no cell lines available for the study of PBoV, and animal model experiments have not been described. This review summarizes the current state of knowledge about PBoV, including the epidemiology, evolution analysis, detection methods, pathogenesis and public health concerns.
猪博卡病毒（PBoV）是一种单链 DNA 病毒，属于细小病毒科细小博卡病毒属。它是与断奶后多系统衰弱综合征（PMWS）病猪的淋巴结中发现的猪圆环病毒 2 型（PCV2）和转矩噬菌体（TTV）一起于 2009 年在瑞典发现的。PBoV 已在世界各地被报道，主要发生在断奶仔猪中，具有广泛的组织嗜性。由于 PBoV 在健康猪和临床感染猪中均普遍存在，并且主要与其他病毒的合并感染相关，因此 PBoV 的致病性尚不清楚。目前，尚无用于研究 PBoV 的细胞系，也未描述动物模型实验。本综述总结了目前关于 PBoV 的研究进展，包括流行病学、进化分析、检测方法、发病机制和公共卫生关注。
