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2006-2018 年国际癌症研究投资趋势。

Trends in International Cancer Research Investment 2006-2018.

机构信息

London School of Hygiene and Tropical Medicine, London, United Kingdom.

Anticancer Fund, Brabant, Belgium.

出版信息

JCO Glob Oncol. 2021 Apr;7:602-610. doi: 10.1200/GO.20.00591.

Abstract

The International Cancer Research Partnership (ICRP) is an active network of cancer research funding organizations, sharing information about funded research projects in a common database. Data are publicly available to enable the cancer research community to find potential collaborators and avoid duplication. This study presents an aggregated analysis of projects funded by 120 partner organizations and institutes in 2006-2018, to highlight trends in cancer research funding. Overall, the partners' funding for cancer research increased from $5.562 billion (bn) US dollars (USD) in 2006 to $8.511bn USD in 2018, an above-inflation increase in funding. Analysis by the main research focus of projects using Common Scientific Outline categories showed that Treatment was the largest investment category in 2018, followed by Early Detection, Diagnosis, and Prognosis; Cancer Biology; Etiology; Control, Survivorship, and Outcomes; and Prevention. Over the 13 years covered by this analysis, research funding into Treatment and Early Detection, Diagnosis, and Prognosis had increased in terms of absolute investment and as a proportion of the portfolio. Research funding in Cancer Biology and Etiology declined as a percentage of the portfolio, and funding for Prevention and Control, Survivorship and Outcomes remained static. In terms of cancer site-specific research, funding for breast cancer and colorectal cancer had increased in absolute terms but declined as a percentage of the portfolio. By contrast, investment for brain cancer, lung cancer, leukemia, melanoma, and pancreatic cancer increased both in absolute terms and as a percentage of the portfolio.

摘要

国际癌症研究合作组织(ICRP)是一个由癌症研究资助组织组成的活跃网络,在一个共同的数据库中共享资助研究项目的信息。数据是公开的,以便癌症研究界能够找到潜在的合作者并避免重复。本研究对 2006-2018 年 120 个合作组织和机构资助的项目进行了汇总分析,以突出癌症研究资助的趋势。总的来说,合作伙伴对癌症研究的资助从 2006 年的 55.62 亿美元增加到 2018 年的 851.1 亿美元,资金呈通货膨胀以上的增长。根据使用通用科学大纲类别对项目的主要研究重点进行的分析表明,2018 年治疗是最大的投资类别,其次是早期发现、诊断和预后;癌症生物学;病因学;控制、生存和结果;以及预防。在本分析涵盖的 13 年中,治疗和早期发现、诊断和预后的研究资金在绝对投资和作为投资组合的比例方面都有所增加。癌症生物学和病因学的研究资金在投资组合中的比例下降,而预防和控制、生存和结果的资金保持不变。就特定癌症部位的研究而言,乳腺癌和结直肠癌的资金在绝对数额上有所增加,但在投资组合中的比例有所下降。相比之下,脑癌、肺癌、白血病、黑色素瘤和胰腺癌的投资在绝对数额和投资组合中的比例都有所增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65f1/8162963/cd18b63a9312/go-7-go.20.00591-g001.jpg

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