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灾难情况下的肾脏问题。

Kidney problems in disaster situations.

作者信息

Vanholder Raymond, Sükrü Sever Mehmet, Lameire Norbert

机构信息

Nephrology Section, Department of Internal Medicine, Ghent University Hospital, 10, Corneel Heymanslaan, B9000 Gent, Belgium.

Department of Nephrology, Istanbul School of Medicine, Istanbul University, Millet Caddesi, 34093 Istanbul, Turkey.

出版信息

Nephrol Ther. 2021 Apr;17S:S27-S36. doi: 10.1016/j.nephro.2020.02.009.

Abstract

Mass disasters, particularly earthquakes, cause many medical problems, including kidney problems, but an organized approach to cope with them was initiated only at the end of previous century, subsequent to the Armenian Spitak earthquake in 1988. Originally, interventions were focused on acute kidney injury (AKI) following crush injury and rhabdomyolysis in victims who had been trapped under the debris of collapsed buildings. However, similar problems were also registered in the context of other catastrophic events, especially man-made disasters like wars and torture. Other kidney-related problems, such as the preservation of treatment continuity in chronic kidney disease (CKD), especially in maintenance dialysis patients, deserved attention as well. Specific therapeutic principles apply to disaster-related kidney problems and these may differ from usual day-to-day clinical practice. Those approaches have been formulated in global and specific country-related guidelines and recommendations. It is clear that a well-conceived and organized management of kidney diseases in disasters benefits outcomes. Furthermore, it may be useful if the model and philosophy that were applied over the last three decades could be adapted by broadening the scope of disasters leading to intervention. Actions should be guided and coordinated by a panel of experts steering ad hoc interventions, rather than applying the "old" static model where a single coordinating center instructs and uses volunteers listed long before a potential event occurs.

摘要

大规模灾难,尤其是地震,会引发诸多医疗问题,包括肾脏问题,但直到上世纪末,在1988年亚美尼亚斯皮塔克地震之后,才开始采取有组织的应对方法。最初,干预措施主要针对被困在倒塌建筑物废墟下的受害者因挤压伤和横纹肌溶解导致的急性肾损伤(AKI)。然而,在其他灾难性事件中,尤其是战争和酷刑等人为灾难中,也出现了类似问题。其他与肾脏相关的问题,比如慢性肾脏病(CKD),尤其是维持性透析患者治疗连续性的维持,也值得关注。针对与灾难相关的肾脏问题有特定的治疗原则,这些原则可能与日常临床实践有所不同。这些方法已在全球及特定国家相关的指南和建议中得以制定。显然,对灾难中肾脏疾病进行精心构思和组织的管理有利于改善治疗结果。此外,如果能通过扩大导致干预的灾难范围来调整过去三十年所应用的模式和理念,可能会有所帮助。行动应由一个指导临时干预措施的专家小组来指导和协调,而不是采用“旧的”静态模式,即由单一协调中心在潜在事件发生前很久就对列出的志愿者进行指示和调配。

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