Kamynina T V, Iakovlev A Iu, Klimovich V B
Eksp Onkol. 1988;10(2):66-9.
A model of the Markov stochastic reproduction and death process is studied as applied to the analysis of time intervals necessary for the experimental tumours to achieve the fixed size. The analysis results have shown nonstationarity of the tumour growth processes during early stages of the tumour development. The presence of such a nonstationarity makes the experimental data interpretation difficult when applying the traditional approach to the tumour cell population kinetics.
研究了马尔可夫随机繁殖和死亡过程模型，该模型应用于分析实验性肿瘤达到固定大小所需的时间间隔。分析结果表明，在肿瘤发展的早期阶段，肿瘤生长过程具有非平稳性。这种非平稳性的存在使得在应用传统方法分析肿瘤细胞群体动力学时，对实验数据的解释变得困难。
