Sandstad E, Maehle B O, Hartveit F
Department of Pathology, Gade Institute, University of Bergen, Norway.
Eur J Gynaecol Oncol. 1988;9(3):204-8.
Over a 5 1/2 yr study period lesions leading to biopsy were reported in 902 of 3.937 women (23%) with a record of cervical neoplasia, compared to 1,142 of 13,030 controls (9%). This applied irrespective of the severity of the cervical lesion. In women with a record of cervical neoplasia, again irrespective of the severity of the lesion, relatively more lesions were seen in other organs in the younger age groups (45 yrs and less). In contrast the number of such lesions increased with age in the controls. While the present study gives no indication of the possible nature of the implied link between cervical neoplasia and the other lesions involved, it is suggested that the possibility of a common virus aetiology should be explored.
在一项为期5年半的研究中，有宫颈肿瘤记录的3937名女性中有902人（23%）报告了导致活检的病变，相比之下，13030名对照中有1142人（9%）出现此类病变。这与宫颈病变的严重程度无关。在有宫颈肿瘤记录的女性中，同样与病变严重程度无关，较年轻年龄组（45岁及以下）的其他器官中出现的病变相对更多。相比之下，对照组中此类病变的数量随年龄增加而增多。虽然本研究未表明宫颈肿瘤与所涉及的其他病变之间潜在联系的可能性质，但建议应探究共同病毒病因的可能性。
