Hartveit F
Department of Pathology, Gade Institute, University of Bergen, Norway.
Oncology. 1988;45(2):103-6. doi: 10.1159/000226542.
Association is reported in a series of 805 patients between cervical dysplasia and the occurrence of lesions in other organs, in particular the skin. The occurrence of associated lesions in these patients was markedly in excess of that in case-matched controls. It was not related to the increased frequency of gynaecological investigation in patients with cervical dysplasia. Pigmented naevi were the most common associated lesions, occurring before and after the diagnosis of cervical dysplasia. Three cases of malignant melanoma were seen in the test group. Gynaecological lesions were also common. The findings are discussed in the light of recent work on viral synergism in genital neoplasia.
在805例患者中报告了宫颈发育异常与其他器官尤其是皮肤病变发生之间的关联。这些患者中相关病变的发生率明显高于病例匹配对照组。这与宫颈发育异常患者妇科检查频率增加无关。色素痣是最常见的相关病变，在宫颈发育异常诊断之前和之后均有发生。试验组中发现了3例恶性黑色素瘤。妇科病变也很常见。根据近期关于生殖器肿瘤中病毒协同作用的研究对这些发现进行了讨论。
