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早期播散性莱姆病中一例罕见的班沃思综合征病例

A Unique Case of Bannwarth Syndrome in Early Disseminated Lyme Disease.

作者信息

Omotosho Yetunde B, Sherchan Robin, Ying Grace W, Shayuk Maryna

机构信息

Internal Medicine, Chicago Medical School Internal Medicine Residency Program at Northwestern Mchenry Hospital, McHenry, USA.

Internal Medicine, Chicago Medical School Internal Medicine Residency Program at Northwestern McHenry Hospital, McHenry, USA.

出版信息

Cureus. 2021 Apr 25;13(4):e14680. doi: 10.7759/cureus.14680.

DOI:10.7759/cureus.14680
PMID:33912367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8071476/
Abstract

Lyme borreliosis is a multisystem inflammatory disease caused by the spirochete ( and transmitted through the tick. Nervous system involvement is known as Lyme neuroborreliosis; it only occurs in disseminated Lyme disease and is manifested by the classic triad of meningitis, cranial neuritis, and radiculoneuritis. Timeline is a significant factor when staging Lyme manifestations. However, certain cases do not follow the typical presentation timelines described in most literature. We report a case of a 66-year-old male who presented with progressively worsening generalized body aches, severe fatigue, and new-onset urine retention for two weeks. Physical examination revealed severe pain with neck flexion and lying supine and diminished deep tendon reflexes bilaterally. Laboratory data revealed a positive Lyme immunoglobulin (Ig) M antibody with lymphocytic pleocytosis on lumbar puncture. He was treated with intravenous (IV) ceftriaxone for early disseminated Lyme disease. His radicular pain responded well to therapy, and he regained full bladder function. Bannwarth syndrome (BWS) is a term applied to the constellation of painful radiculoneuritis characterized as severe, burning, often dermatomal pain. In most cases, BWS affects the limbs, with only a few reported cases of sacral radiculitis causing neurogenic urinary dysfunction. Early recognition of this rare presentation associated with Lyme disease and treatment with antibiotics can prevent disease progression and detrimental neurological sequelae.

摘要

莱姆病是一种由螺旋体引起的多系统炎症性疾病(通过蜱传播)。神经系统受累称为莱姆神经疏螺旋体病;它仅发生在播散性莱姆病中,表现为脑膜炎、颅神经炎和神经根神经炎的典型三联征。在对莱姆病表现进行分期时,时间线是一个重要因素。然而,某些病例并不遵循大多数文献中描述的典型表现时间线。我们报告一例66岁男性病例,该患者出现全身疼痛逐渐加重、严重疲劳以及新发尿潴留两周。体格检查发现颈部屈曲和仰卧时疼痛剧烈,双侧深腱反射减弱。实验室检查数据显示莱姆免疫球蛋白(Ig)M抗体阳性,腰椎穿刺显示淋巴细胞增多。他因早期播散性莱姆病接受了静脉注射头孢曲松治疗。他的神经根性疼痛对治疗反应良好,膀胱功能完全恢复。班诺瓦特综合征(BWS)是一个用于描述以严重、灼痛、常为皮节性疼痛为特征的疼痛性神经根神经炎的术语。在大多数情况下,BWS影响四肢,仅有少数骶神经根炎病例报告导致神经源性排尿功能障碍。早期识别这种与莱姆病相关的罕见表现并使用抗生素治疗可预防疾病进展和有害的神经后遗症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc7d/8071476/c399ce5b3f72/cureus-0013-00000014680-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc7d/8071476/c399ce5b3f72/cureus-0013-00000014680-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc7d/8071476/c399ce5b3f72/cureus-0013-00000014680-i01.jpg

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