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儿童胰岛素依赖型糖尿病的地理分布模式。糖尿病流行病学国际研究小组。

Geographic patterns of childhood insulin-dependent diabetes mellitus. Diabetes Epidemiology Research International Group.

出版信息

Diabetes. 1988 Aug;37(8):1113-9.

PMID:3391346
Abstract

Population-based registries of insulin-dependent diabetes mellitus (IDDM) worldwide have reached the critical mass needed to investigate global patterns of the disease. International collaboration of 24 registries from 15 countries resulted in the first set of standardized incidence measures among divergent areas and ethnic groups. The average annual age-adjusted incidence under age 15 yr ranged from 1.7/100,000 person-yr in Hokkaido, Japan, to 29.5/100,000 person-yr in Finland during the years 1978-1980. The geographic differences in IDDM in childhood are rarely seen among chronic diseases. It appears that the risk for IDDM is determined by factor(s) correlated to the average yearly temperature of environment and to the ethnicity of the population at risk.

摘要

全球基于人群的胰岛素依赖型糖尿病(IDDM)登记系统已达到调查该疾病全球模式所需的临界规模。来自15个国家的24个登记系统开展国际合作,得出了不同地区和种族群体中的第一组标准化发病率指标。在1978 - 1980年期间,15岁以下年龄调整后的年平均发病率范围为:日本北海道每10万人年1.7例,芬兰每10万人年29.5例。儿童期IDDM的地理差异在慢性病中很少见。看来,IDDM的风险由与环境年平均温度以及高危人群种族相关的因素决定。

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