Dahl-Jørgensen K, Joner G, Hanssen K F
Aker Diabetes Research Center, Aker University Hospital, Oslo, Norway.
Diabetes Care. 1991 Nov;14(11):1081-3. doi: 10.2337/diacare.14.11.1081.
To compare age-standardized incidence rates of diabetes in children 0-14 yr of age and cows' milk consumption in various countries.
Ecological correlation study. Only incidence rates from diabetes registries carefully validated by the Diabetes Epidemiology Research International Study Group were used-Finland, Sweden, Norway, Great Britain, Denmark, United States, New Zealand, Netherlands, Canada, France, Israel, and Japan. Data on fluid cows' milk consumption in corresponding countries were obtained from the International Dairy Federation.
Correlation between milk consumption and incidence of insulin-dependent diabetes mellitus (IDDM) was 0.96. The data fit a linear regression model, and analysis showed that 94% of the geographic variation in incidence might be explained by differences in milk consumption.
The results support the hypothesis that cows' milk may contain a triggering factor for the development of IDDM.
比较不同国家0至14岁儿童糖尿病的年龄标准化发病率及牛奶消费量。
生态关联研究。仅采用经国际糖尿病流行病学研究组织仔细验证的糖尿病登记处的发病率数据——芬兰、瑞典、挪威、英国、丹麦、美国、新西兰、荷兰、加拿大、法国、以色列和日本。相应国家的液态牛奶消费量数据来自国际乳品联合会。
牛奶消费量与胰岛素依赖型糖尿病（IDDM）发病率之间的相关性为0.96。数据符合线性回归模型，分析表明发病率的94%的地理差异可能由牛奶消费量差异所解释。
结果支持牛奶可能含有引发IDDM的触发因素这一假说。
