Karthika I K, Gulla Krishna Mohan, John Joseph, Satapathy Amit Kumar, Sahu Suchanda, Behera Bijayini, Mishra Priyadarshini
Department of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Department of Biochemistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Indian J Ophthalmol. 2021 May;69(5):1319-1321. doi: 10.4103/ijo.IJO_52_21.
Multi Inflammatory Syndrome (MIS-C) associated with Corona Virus Disease (COVID) in children and young adults presents with a varied clinical spectrum; from that mimicking Kawasaki disease (KD), Incomplete Kawasaki disease to even Hemophagocytic Lymphohistiocytosis. A 14-year-old girl, presented to us, with headache, fever, bilateral uveitis, unilateral cervical lymphadenopathy, oral mucosal changes and abdominal pain. A disproportionate increase in inflammatory markers and Interleukin - 6, in the setting of a negative COVID real-time reverse transcription polymerase chain reaction (RTPCR) and significantly elevated COVID antibody titre confirmed our diagnosis. She was treated with intravenous Immunoglobulin and oral steroids with which she recovered. We want to highlight considering the possibility of MIS-C in children presenting with uveitis at a time when COVID-19 has been conquering the world with community spread.
儿童和青年中与冠状病毒病（COVID）相关的多炎症综合征（MIS-C）具有多种临床症状；从类似川崎病（KD）、不完全川崎病到噬血细胞性淋巴组织细胞增生症。一名14岁女孩前来就诊，有头痛、发热、双侧葡萄膜炎、单侧颈部淋巴结肿大、口腔黏膜改变和腹痛。在新冠病毒实时逆转录聚合酶链反应（RTPCR）结果为阴性且新冠抗体滴度显著升高的情况下，炎症标志物和白细胞介素-6不成比例地增加，从而确诊。她接受了静脉注射免疫球蛋白和口服类固醇治疗，随后康复。在新冠疫情全球社区传播之际，我们想强调对于出现葡萄膜炎的儿童要考虑到MIS-C的可能性。
