Montoro-Dasi Laura, Villagra Arantxa, Sevilla-Navarro Sandra, Pérez-Gracia Maria Teresa, Vega Santiago, Marin Clara
Instituto de Ciencia y Tecnología Animal, Universidad Politécnica de Valencia, 46022 Valencia, Spain.
Centro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Castellón, Spain.
Animals (Basel). 2021 Apr 3;11(4):1005. doi: 10.3390/ani11041005.
New measures applied to reduce antimicrobial resistances (AMR) at field level in broiler production are focused on improving animals' welfare and resilience. However, it is necessary to have better knowledge of AMR epidemiology. Thus, the aim of this study was to evaluate AMR and multidrug resistance (MDR) dynamics during the rearing of broilers under commercial (33 kg/m density and max. 20 ppm ammonia) and improved (17 kg/m density and max. 10 ppm ammonia) farm conditions. Day-old chicks were housed in two poultry houses (commercial vs. improved), and no antimicrobial agents were administered at any point. Animals were sampled at arrival day, mid-period and at slaughter day. High AMR rates were observed throughout rearing. No statistical differences were observed between groups. Moreover, both groups presented high MDR at slaughter day. These results could be explained by vertical or horizontal resistance acquisition. In conclusion, AMR and MDR are present throughout rearing. Moreover, although a lower level of MDR was observed at mid-period in animals reared under less intensive conditions, no differences were found at the end. In order to reduce the presence of AMR bacteria in poultry, further studies are needed to better understand AMR acquisition and prevalence in differing broiler growing conditions.
应用于肉鸡生产现场以降低抗菌药物耐药性（AMR）的新措施着重于改善动物福利和恢复力。然而，有必要更深入了解AMR流行病学。因此，本研究的目的是评估在商业养殖（密度33 kg/m²和最大20 ppm氨）和改良养殖（密度17 kg/m²和最大10 ppm氨）农场条件下肉鸡饲养过程中的AMR和多重耐药性（MDR）动态变化。一日龄雏鸡饲养在两个禽舍（商业养殖与改良养殖）中，在任何时间点均未使用抗菌剂。在雏鸡抵达日、饲养中期和屠宰日对动物进行采样。在整个饲养过程中均观察到较高的AMR发生率。两组之间未观察到统计学差异。此外，两组在屠宰日时均呈现出较高的MDR。这些结果可以通过垂直或水平耐药性获得来解释。总之，在整个饲养过程中均存在AMR和MDR。此外，尽管在饲养强度较低条件下饲养的动物在中期观察到较低水平的MDR，但在末期未发现差异。为了减少家禽中AMR细菌的存在，需要进一步研究以更好地了解不同肉鸡生长条件下AMR的获得和流行情况。
