Cho Dong-Hyuk, Lee Sun Ju, Jae Sae Young, Kim Woo Joo, Ha Seong Jun, Gwon Jun Gyo, Choi Jimi, Kim Dong Wook, Kim Jang Young
Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.
Department of Big Data Strategy, National Health Insurance Service, Wonju 26464, Korea.
J Clin Med. 2021 Apr 6;10(7):1539. doi: 10.3390/jcm10071539.
Regular physical activity (PA) is known to reduce the risk of serious community-acquired infections. We examined the association of PA with the morbidity and mortality resulting from coronavirus disease (COVID-19) infection in the South Korean population. Patients who tested positive for severe acute respiratory coronavirus 2 and who underwent public health screening between 2014 and 2017 ( = 6288) were included. Age- and sex-matched controls ( = 125,772) were randomly selected from the Korean National Health Insurance Service database. Leisure-time PA was assessed using a self-reported questionnaire. The mean PA levels were lower in the patient than in the control group (558.2 ± 516.3 vs. 580.2 ± 525.7 metabolic equivalent of task (MET)-min/week, = 0.001). Patients with moderate to vigorous PA (MVPA) were associated with a lower risk of COVID-19 morbidity (odds ratio (OR), 0.90; 95% confidence interval (CI), 0.86-0.95). In addition, a standard deviation (SD) increment in MET/week (525.3 MET-min/week) was associated with a 4% decrease in the risk of COVID-19 morbidity (OR, 0.96; 95% CI, 0.93-0.99). MVPA and an SD increment in MET/week were associated with lower mortality (MVPA: OR, 0.47; 95% CI, 0.26-0.87; per SD increment: OR, 0.65; 95% CI, 0.48-0.88). Higher levels of regular PA were associated with a lower risk of COVID-19 infection and mortality, highlighting the importance of maintaining appropriate levels of PA along with social distancing amid the COVID-19 pandemic.
众所周知，经常进行体育活动（PA）可降低严重社区获得性感染的风险。我们研究了韩国人群中体育活动与冠状病毒病（COVID-19）感染导致的发病率和死亡率之间的关联。纳入了2014年至2017年期间严重急性呼吸冠状病毒2检测呈阳性且接受公共卫生筛查的患者（n = 6288）。从韩国国民健康保险服务数据库中随机选取年龄和性别匹配的对照（n = 125,772）。使用自我报告问卷评估休闲时间的体育活动。患者组的平均体育活动水平低于对照组（558.2±516.3与580.2±525.7代谢当量任务（MET）-分钟/周，P = 0.001）。中度至剧烈体育活动（MVPA）的患者患COVID-19发病的风险较低（优势比（OR），0.90；95%置信区间（CI），0.86 - 0.95）。此外，每周MET增加一个标准差（SD）（525.3 MET-分钟/周）与COVID-19发病风险降低4%相关（OR，0.96；95% CI，0.93 - 0.99）。MVPA和每周MET增加一个标准差与较低的死亡率相关（MVPA：OR，0.47；95% CI，0.26 - 0.87；每增加一个SD：OR，0.65；95% CI，0.48 - 0.88）。较高水平的经常体育活动与较低的COVID-19感染和死亡率风险相关，凸显了在COVID-19大流行期间保持适当体育活动水平以及保持社交距离的重要性。
