Gentile Eleonora, Delussi Marianna, Abagnale Chiara, Caponnetto Valeria, De Cesaris Francesco, Frattale Ilaria, Guaschino Elena, Marcinnò Andrea, Ornello Raffaele, Pistoia Francesca, Putortì Alessia, Candida Giusy, Roveta Fausto, Lupi Chiara, Coppola Gianluca, Prudenzano Addolorata Maria Pia, Rainero Innocenzo, Sances Grazia, Roca Maria Elena, Trojano Maria, Pierelli Francesco, Geppetti Pierangelo, Sacco Simona, de Tommaso Marina
Applied Neurophysiology and Pain Unit, SMBNOS Department, Bari Aldo Moro University, 70121 Bari, Italy.
Headache Center, Sapienza Rome University, 04100 Latina, Italy.
Brain Sci. 2021 Apr 10;11(4):482. doi: 10.3390/brainsci11040482.
The study aims to assess the impact of the second COVID-19 pandemic wave on migraine characteristics.
This is an observational cross-sectional study conducted on migraine patients previously interviewed during the first Italian pandemic outbreak. A second structured telephone interview was conducted between 20 November 2020 and 18 January 2021. We compared migraine characteristics among T0 (before pandemic), T1 (during the first pandemic phase), and T2 (during the second pandemic phase).
Among the 433 patients interviewed during the first pandemic phase, 304 cases were finally considered. One hundred forty-eight patients had a control visit between March 2020 and December 2020, 120 had an in-person visit, 14 by phone, the remainder used telemedicine software provided by the hospital. Frequency of headache, number of symptomatic drugs and headache intensity worsened during T2, compared to T0 and T1, especially in episodic migraine. Headache intensity increased relating to the negative emotional impact of the pandemic. Migraine management during the pandemic did not influence the clinical outcome.
The prolongation of the pandemic seems to have a negative impact on migraine evolution. The arousal and negative psychological behavior toward the COVID-19 outbreak seem to worsen migraine.
本研究旨在评估第二波新冠疫情对偏头痛特征的影响。
这是一项针对在意大利首次疫情爆发期间接受过访谈的偏头痛患者进行的观察性横断面研究。于2020年11月20日至2021年1月18日期间进行了第二次结构化电话访谈。我们比较了T0（疫情前）、T1（第一波疫情期间）和T2（第二波疫情期间）的偏头痛特征。
在第一波疫情期间接受访谈的433例患者中，最终纳入304例。148例患者在2020年3月至12月期间进行了对照访视，120例进行了面对面访视，14例通过电话访视，其余使用医院提供的远程医疗软件。与T0和T1相比，T2期间头痛频率、对症药物数量和头痛强度恶化，尤其是发作性偏头痛。头痛强度增加与疫情的负面情绪影响有关。疫情期间的偏头痛管理并未影响临床结果。
疫情的延长似乎对偏头痛的演变有负面影响。对新冠疫情爆发的唤醒和负面心理行为似乎会使偏头痛恶化。
