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非酒精性脂肪性肝病与心血管合并症:病理生理联系、诊断及治疗管理

Non-Alcoholic Fatty Liver Disease and Cardiovascular Comorbidities: Pathophysiological Links, Diagnosis, and Therapeutic Management.

作者信息

Jichitu Alexandra, Bungau Simona, Stanescu Ana Maria Alexandra, Vesa Cosmin Mihai, Toma Mirela Marioara, Bustea Cristiana, Iurciuc Stela, Rus Marius, Bacalbasa Nicolae, Diaconu Camelia Cristina

机构信息

Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.

Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.

出版信息

Diagnostics (Basel). 2021 Apr 12;11(4):689. doi: 10.3390/diagnostics11040689.

Abstract

Non-alcoholic fatty liver disease (NAFLD) has a growing prevalence in recent years. Its association with cardiovascular disease has been intensively studied, and certain correlations have been identified. The connection between these two entities has lately aroused interest regarding therapeutic management. In order to find the best therapeutic options, a detailed understanding of the pathophysiology that links (NAFLD) to cardiovascular comorbidities is needed. This review focuses on the pathogenic mechanisms that are behind these two diseases and on the therapeutic management available at this time.

摘要

非酒精性脂肪性肝病(NAFLD)近年来的患病率呈上升趋势。其与心血管疾病的关联已得到深入研究,并已确定了某些相关性。这两种疾病之间的联系最近引起了人们对治疗管理的兴趣。为了找到最佳治疗方案,需要详细了解将NAFLD与心血管合并症联系起来的病理生理学。本综述重点关注这两种疾病背后的致病机制以及目前可用的治疗管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1e6/8069361/81e7acce4c3e/diagnostics-11-00689-g001.jpg

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