Muhammad Umar Abubakar, Yasid Nur Adeela, Daud Hassan Mohd, Shukor Mohd Yunus
Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia (UPM), Seri Kembangan 43400, Malaysia.
Department of Biological Sciences, Faculty of Science, Gombe State University, P.M.B. 027, Gombe State 760214, Nigeria.
Animals (Basel). 2021 Apr 22;11(5):1209. doi: 10.3390/ani11051209.
The development of glyphosate-resistant genetically modified organisms (GMO) has increased the use of herbicide glyphosate by several magnitudes in recent years. It is now the most commonly used pesticide globally that affects aquatic habitats, especially fish. This study aims to add new knowledge on the effect of technical grade glyphosate on several toxicity parameters and to identify the most effective parameter in predicting technical grade glyphosate chronic toxicity (seven weeks) to fish, especially Malaysia's heavily farmed red tilapia. The results show that a relatively high concentration of technical grade glyphosate is needed to induce significant changes in all tested parameters. However, the results also indicate that the bodyweight index is the most sensitive toxicity parameter in that a reduction in body weight was observed at 25 mg/L of glyphosate. Negative correlations between the glyphosate concentration and toxicity parameters such as specific growth rate (SGR), hepato-somatic index (HIS), and gonado-somatic index (GSI) were observed. The fish condition factor and feed conversion ratio were found not to be affected at the highest glyphosate concentration tested (150 mg/L). To conclude, crossbred red tilapia () is one potential species for evaluating the toxic effects of technical grade glyphosate on fish.
近年来,抗草甘膦转基因生物(GMO)的发展使除草剂草甘膦的使用量增加了几个数量级。它现在是全球最常用的影响水生栖息地,尤其是鱼类的农药。本研究旨在增加关于技术级草甘膦对几个毒性参数影响的新知识,并确定预测技术级草甘膦对鱼类(尤其是马来西亚大量养殖的红罗非鱼)慢性毒性(七周)的最有效参数。结果表明,需要相对高浓度的技术级草甘膦才能在所有测试参数中引起显著变化。然而,结果还表明,体重指数是最敏感的毒性参数,在草甘膦浓度为25mg/L时观察到体重下降。观察到草甘膦浓度与特定生长率(SGR)、肝体指数(HIS)和性腺体指数(GSI)等毒性参数之间呈负相关。在测试的最高草甘膦浓度(150mg/L)下,发现鱼类状况因子和饲料转化率不受影响。总之,杂交红罗非鱼()是评估技术级草甘膦对鱼类毒性作用的一种潜在物种。