Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
Division of Gastroenterology, Mayo Clinic, Rochester, MN, USA.
Curr Nutr Rep. 2018 Dec;7(4):329-334. doi: 10.1007/s13668-018-0243-0.
Obesity is a life-limiting disease that is associated with a number of co-morbidities. Bariatric surgery remains the most efficacious and durable weight loss method available to patients. However, a significant percentage of patients can regain weight resulting in frustration, depression, and return of obesity-related co-morbidities. The present review provides an overview of the most common therapeutic modalities available to combat weigh regain after weight loss surgery.
Given the high percentage of patients with weight regain after surgery, significant effort has been placed on developing treatment options in the last few years. Tremendous work has taken place in the realm of cognitive behavior therapy, appetite suppressants, and endoscopic procedures with the hope of reducing the need for revision surgery which can be associated with significant complications. Weight regain is unfortunately a common phenomenon associated with all weight loss modalities including bariatric surgery. We now have a number of treatment options that can reverse the weight loss trend.
肥胖是一种危及生命的疾病，与许多合并症有关。减重手术仍然是患者最有效和持久的减肥方法。然而，相当一部分患者会体重反弹，导致沮丧、抑郁和肥胖相关合并症的复发。本综述概述了目前用于对抗减肥手术后体重反弹的最常见治疗方法。
鉴于手术后体重反弹的患者比例很高，近年来人们在开发治疗方法方面做出了巨大努力。认知行为疗法、食欲抑制剂和内镜手术领域取得了巨大进展，希望减少需要进行可能会带来严重并发症的再次手术。不幸的是，体重反弹是所有减肥方法（包括减重手术）都存在的一个常见现象。我们现在有许多治疗选择可以逆转减肥趋势。
