自身免疫性胰腺炎诊断生物标志物综述：我们目前的进展如何？
Review of Diagnostic Biomarkers in Autoimmune Pancreatitis: Where Are We Now?
作者信息
Yokode Masataka, Shiokawa Masahiro, Kodama Yuzo
机构信息
Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
出版信息
Diagnostics (Basel). 2021 Apr 25;11(5):770. doi: 10.3390/diagnostics11050770.
Autoimmune pancreatitis (AIP) is a pancreatic manifestation of an IgG4-related disease (IgG4-RD). AIP lacks disease-specific biomarkers, and therefore, it is difficult to distinguish AIP from malignancies, especially pancreatic cancer. In this review, we have summarized the latest findings on potential diagnostic biomarkers for AIP. Many investigations have been conducted, but no specific biomarkers for AIP are identified. Therefore, further studies are required to identify accurate diagnostic biomarkers for AIP.
自身免疫性胰腺炎（AIP）是IgG4相关性疾病（IgG4-RD）的胰腺表现形式。AIP缺乏疾病特异性生物标志物，因此，很难将AIP与恶性肿瘤，尤其是胰腺癌区分开来。在本综述中，我们总结了关于AIP潜在诊断生物标志物的最新发现。已经进行了许多研究，但尚未确定AIP的特异性生物标志物。因此，需要进一步研究以确定AIP的准确诊断生物标志物。
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